BACKGROUND Drug abuse is a major public health problem. Some believe that when dissociation fails to defend against emotional, physical, or sexual trauma, the person will find relief from unpleasant thoughts and emotions in opium use. On the other hand, personality disorders are considered as important predictors of treatment outcomes in drug abusers. Due to lack of adequate research in this re...

Recent advances in neurosciences urge us to reconsider the existing links between organic causes and clinical findings of dissociative disorders. The clinical heterogeneity of these disorders is well known. Furthermore, the present neurobiological data are specific to only some dissociative disorders, which question the usefulness of an integrative approach for these data. Several studies sugge...

Recent studies have suggested an association between childhood physical and sexual abuse and adult dissociative experiences. The purpose of this study was to determine the relationship of both childhood and adult-onset abuse and their characteristics for adult dissociative symptoms. One hundred forty-four psychiatric outpatients completed self-report questionnaires on measures of dissociation (...

BACKGROUND There is a great deal of medical literature suggesting that substance use disorder is a serious clinical concern, affecting general population and associated with considerable economic, societal, and personal costs. OBJECTIVES This study sought to clarify the relationship between early trauma, dissociative experience, and suicide ideation as predictive factors of active and passive...

OBJECTIVE Smaller hippocampal volume has been reported in several stress-related psychiatric disorders, including posttraumatic stress disorder (PTSD), borderline personality disorder with early abuse, and depression with early abuse. Patients with borderline personality disorder and early abuse have also been found to have smaller amygdalar volume. The authors examined hippocampal and amygdala...

OBJECTIVE To campare the family functioning, level of depression, anxiety and histrionic personality traits among depressive and dissociative (conversion) patients. STUDY DESIGN A cross-sectional study. PLACE AND DURATION OF STUDY The Psychiatry Unit of Government Lady Reading Hospital, Peshawar, on depressive and dissociative (conversion) patients admitted from January to May 2004. METHO...

BACKGROUND Dissociation has been recognized as a relevant factor within the context of traumatization. Since childhood maltreatment as well as child birth can be regarded as a potential trauma, this study examined dissociation in a sample of 58 young mothers with a history of abuse in comparison to a control group. METHODS All women with newborn children were contacted by mail and presented w...

We present an evidence-based clinical practice guideline for the administration of the dissociative agent ketamine for emergency department pediatric procedural sedation and analgesia. Substantial research in recent years has necessitated updates and revisions to the widely disseminated 1990 recommendations. We critically discuss indications, contraindications, personnel requirements, monitorin...

X-ray photoelectron and electron energy loss spectroscopic (XPS-EELS) studies reveal that the following species are present when a mixture of CO2 and water vapour is exposed to the clean Mg(100) surface at 110K: CO3(a), C(a) CH(a), OH(a). The reactive chemisorptions of CO2 and H2O vapour coadsorbed on a Mg surface ...