statement of problem: early diagnoses of oral malignancies and pre-malignancies have direct effect in the outcome of these lesions. therefore the techniques for early diagnosis have been considered as useful method in practice. purpose: the aim of this study was to evaluate the reliability of oratest and generic toluidine blue (gtb) in the detection of oral malignancy and premalignancy. materia...

OBJECTIVE The present study was designed to explore the clinical values of microRNA-129 (miR-129) expression in peripheral blood mononuclear cells for prostate cancer patients and the role of miR-129 in the proliferation of prostate cancer. METHODS The peripheral blood mononuclear cells were isolated form blood simple from 98 patients confirmed with prostate cancer and 56 matched healthy volu...

Introduction: Development of brain edema following focal cerebral ischemia exacerbates primary ischemic injury. Blood brain barrier (BBB) opening is an important part of edema named as vasogenic brain edema. In this study, quantitative alterations of BBB permeability is experimentally evaluated using transient focal cerebral ischemia in the rat. Methods: Two groups of male rats (ischemic and sh...

Noble gas pulmonary magnetic resonance imaging (MRI) is transitioning away from (3)He to (129)Xe gas, but the physiological/clinical relevance of (129)Xe apparent diffusion coefficient (ADC) parenchyma measurements is not well understood. Therefore, our objective was to generate (129)Xe MRI ADC for comparison with (3)He ADC and with well-established measurements of alveolar structure and functi...

Gene-targeting techniques to produce null mutations provide a powerful method for evaluating the contribution of particular candidate genes involved in motivation. The embryonic stem cell lines in which homologous recombination is undertaken are derived from 129 mice, but because of the impoverished performance of 129 mice on a number of behavioral tasks, mice chimeric for the mutation are ofte...

In the current survey, the removal of dye from contaminated water was studied by photocatalytic degradation using TiO2 nanoparticles with respect to pH, TiO2 dosage, reaction time, temperature and initial dye concentration. TiO2 nanoparticles were investigated by XRD, FESEM and FT-IR.The RSM was chosen to study the composition effects of input independent factor...

blue nevi are uncommon, asymptomatic lesions of the uterine cervix. these lesions are not often detected clinically or on colposcopy. careful histopathological examination is required. the nevus cells are said to originate from the immature melanoblasts of the neural crest. these lesions need to be differentiated from malignant melanoma and melanosis of the cervix. we present here a case report...