نتایج جستجو برای: dipeptide

تعداد نتایج: 3045  

Journal: :Chemical communications 2012
Jaclyn Raeburn Tom O McDonald Dave J Adams

UV irradiation of a dipeptide gelator in solution with a photoacid generator (PAG) results in the formation of a hydrogel. We demonstrate that photopatterning of these gels using a UV mask is possible.

Journal: :Molecular biology and evolution 1994
J Nielsen A A Peixoto A Piccin R Costa C P Kyriacou D Chalmers

The region of the clock gene period (per) that encodes a repetitive tract of threonine-glycine (Thr-Gly) pairs has been compared between Dipteran species both within and outside the Drosophilidae. All the non-Drosophilidae sequences in this region are short and present a remarkably stable picture compared to the Drosophilidae, in which the region is much larger and extremely variable, both in s...

Journal: :Antimicrobial agents and chemotherapy 2016
Lizah T van der Aart Nicole Lemmens Willem J van Wamel Gilles P van Wezel

The increasing resistance of clinical pathogens against the glycopeptide antibiotic vancomycin, a last-resort drug against infections with Gram-positive pathogens, is a major problem in the nosocomial environment. Vancomycin inhibits peptidoglycan synthesis by binding to the d-Ala-d-Ala terminal dipeptide moiety of the cell wall precursor lipid II. Plasmid-transferable resistance is conferred b...

1997
Michael D. Beachy David Chasman Robert B. Murphy Thomas A. Halgren Richard A. Friesner

Correlated ab initio calculations have been carried out with a parallel version of the PSGVB electronic structure code to obtain relative energetics of a number of conformations of the alanine tetrapeptide. The highest level of theory utilized, local MP2 with the cc-pVTZ(-f) correlation-consistent basis set, has previously been shown to provide accurate conformational energies in comparison wit...

Journal: :PLoS Pathogens 2006
Catherine Chaput Chantal Ecobichon Nadège Cayet Stephen E Girardin Catherine Werts Stéphanie Guadagnini Marie-Christine Prévost Dominique Mengin-Lecreulx Agnès Labigne Ivo G Boneca

The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms. The molecular mechanisms of the morphological transition between these two forms and the role of coccoids remain largely unknown. The peptidoglycan (PG) layer is a major determinant of bacterial cell ...

Journal: :Journal of bacteriology 2004
Astrid P Koudelka Lisa A Hufnagel Gerald B Koudelka

The genes encoding Shiga toxin (stx), the major virulence factor of Shiga toxin-encoding Escherichia coli (STEC) strains, are carried on lambdoid prophages resident in all known STEC strains. The stx genes are expressed only during lytic growth of these temperate bacteriophages. We cloned the gene encoding the repressor of the Shiga toxin-encoding bacteriophage 933W and examined the DNA binding...

2011
Amy F. Roth Irene Papanayotou Nicholas G. Davis

The yeast kinase Yck2 tethers to the cytoplasmic surface of the plasma membrane through dual palmitoylation of its C-terminal Cys-Cys dipeptide, mediated by the Golgi-localized palmitoyl-transferase Akr1. Here, the Yck2 palmitoylation signal is found to consist of three parts: 1) a 10-residue-long, conserved C-terminal peptide (CCTP) that includes the C-terminal Cys-Cys dipeptide; 2) the kinase...

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