diminishing protein aggregation by chaperone is very important factor in medicine and industry. in this paper, itis induced the chaperone ability for 0-casein upon modification of its acidic residues by woodward reagentk(wrk) and examined on lysozyme as a target protein at ph 7.2 and outlined the mechanism for chaperoneability of modified system by uv-vis and fluorescence spectroscopy and theor...

In this work we analyze a class of diminishing 2 × 2 Pólya-Eggenberger urn models with ball replacement matrix M given by M = ` −a 0 c −d´, a, d ∈ N and c ∈ N0. We obtain limit laws for this class of 2 × 2 urns by giving estimates for the moments of the considered random variables. As a special instance we obtain limit laws for the pills problem, proposed by Knuth and McCarthy, which correspond...

The well-known inverse relationship between farm size and productivity is usually explained in terms of diminishing returns with respect to land and other inputs coupled with various types of market frictions that prevent the efficient allocation of land across farms. We show that even in the absence of diminishing returns one can provide an alternative explanation for this phenomenon using end...

We show that even in the absence of diminishing returns in production and technological spillovers, international trade leads to a stable world income distribution. This is because specialization and trade introduce de facto diminishing returns: countries that accumulate capital faster than average experience declining export prices, depressing the rate of return to capital and discouraging fur...

I use data on individual pay and output from Safelite Corp. to estimate a principal-agent model with moral hazard in which the agent has preferences that approximate various specifications of reference dependence, diminishing sensitivity, and loss aversion, as well as the standard case of CARA utility. Estimating the preference parameters via GMM on the incentive and participation constraints s...

Recent efforts to translate basic research to the treatment of clinical disorders have led to a growing interest in exploring mechanisms for diminishing fear. This research has emphasized two approaches: extinction of conditioned fear, examined across species; and cognitive emotion regulation, unique to humans. Here, we sought to examine the similarities and differences in the neural mechanisms...