2-(Methylamino) pyridine (HMAP) reacts with MeLi in THF and generates the lithium salt (LiMAP). Further reaction of [Cu(TMEDS)2][CuCl2] (TMEDA=tetramethylethylenediamine) with one equivalent of this ligand in THF leads to the formation of a yellow dimeric Cu(I) complex, [Cu(MAP)]2. Analytical data, molecular weight, and magnetic susceptibility measurements, ...

Ligand binding to the thrombopoietin receptor is thought to stabilize an active receptor dimer that regulates megakaryocyte differentiation and platelet formation, as well as haematopoietic stem cell renewal. By fusing a dimeric coiled coil in all seven possible orientations to the thrombopoietin receptor transmembrane (TM)-cytoplasmic domains, we show that specific biological effects and in vi...

Fibrous wastes correspond to approximately 54.3 wt.-% of a banana plant. The waste weight is mainly bunches, stems, and leaves. These ligno-cellulosic fibre can be designed tailored yield value added products which exploited by the farmers, exporters weavers. Pectin (plant cement) hemicelluloses (22-25%) found in plant cell walls plate (middle lamella). macromolecules have needs hydrolyzed fast...

Pectinase (Pectin methyl esterase) produced by Aspergillus niger in solid state fermentation of apple pomace using the optimized conditions was partially purified by (NH4)2SO4 fractionation (20-80% concentration). The purified enzyme was found to be stable up to 60 days. It remained heat stable up to 50oC but completely inactivated at 90oC. The partially purified enzyme showed highest activity ...

Enzymatic extraction was investigated to improve the quality of black tea extracts with pretreatment of pectinase and tannase independently, successively and simultaneously. Pectinase improved the extractable-solids-yield (ESY) up to 11.5%, without much of an improvement in polyphenols recovery, while tannase pre-treatment showed a significant improvement in polyphenols recovery (14.3%) along w...

The aim of this study was to evaluate the additional value of dimeric inhibin-A serum concentration in second trimester multiple-marker screening tests for pregnancies affected by Down's syndrome. We anticipated that second trimester maternal serum dimeric inhibin-A concentrations would be altered in pregnancies complicated by fetal Down's syndrome and that dimeric inhibin-A would perform bette...