INTRODUCTION In this study, quasi-three-dimensional (3D) microwell patterns were fabricated with poly (l-lactic acid) for the development of cell-based assays, targeting voltage-gated calcium channels (VGCCs). METHODS AND MATERIALS SH-SY5Y human neuroblastoma cells were interfaced with the microwell patterns and found to grow as two dimensional (2D), 3D, and near two dimensional (N2D), catego...

conclusions we believe that the sh state in chf patients may be associated with the impaired pattern of circulating emps, with the predominantly increased number of apoptotic-derived microparticles. background subclinical hypothyroidism (sh) is diagnosed biochemically by the presence of normal serum free thyroxine concentration, in conjunction with an elevated serum thyroid-stimulating hormone ...

A-type K+ currents are expressed in Xenopus oocytes injected with in vitro-synthesized transcripts from cDNAs for the Drosophila Shaker (Sh) locus. A single Sh gene product, possibly as a multimer, is sufficient for formation of functional A channels. Various Sh RNAs express A currents with distinct kinetic properties. An analysis of structure-function relationships shows that the conserved cen...

In the case of direct-illumination, we represent visibility at each azimuthal direction in the NLP basis, whereas the approach in [SN08] simply stores the maximum blocking angle. In order to construct the SH visibility per azimuthal wedge, we use the NLP-to-SH blending matrices, whereas the approach in [SN08] queries pre-computed 2D tables of linearly blended SH projections of individual SH wed...

Recently, a new alloantigen on IgG Fc receptor type IIIb (FcgRIIIb), SH, was described (Bux et al, Blood 89:1027, 1997). We identified three healthy individuals whose neutrophils reacted positively with the SH antiserum. The neutrophil antigen (NA) phenotype of all three donors was NA(11,21). Analysis of genomic DNA showed that the three donors were positive for the described SH-encoding mutati...

Chronic obstructive pulmonary disease (COPD) is characterized by airway obstruction, inflammation, and mucus hypersecretion, features that are common in bronchitis, emphysema, and often asthma. However, current rodent models do not reflect this human disease. Because genetically predisposed spontaneously hypertensive (SH) rats display phenotypes such as systemic inflammation, hypercoagulation, ...

Shoot N concentration in plants decreases as they get bigger, due to the fact that N accumulates less rapidly than dry matter in plants during the plant growth process, leading to an allometric relationship between shoot N content (N(sh)) and shoot mass (W(sh)): N(sh)=a(W(sh))b. The results obtained on lucerne plants growing either under controlled low density conditions or in dense stands unde...

The effect of an additional chromosome 6 upon recombination in chromosome 9 was investigated in maize. Trisomic 6 plants and their disomic sibs, heterozygous for three loci of chromosome 9 (yg, sh and wx), were testcrossed, and recombination in the regions yg-sh and sh-wx was analyzed. Single exchanges in the sh-wx region and double exchanges were more frequent in trisomics, particularly in fem...

—Rapid increase in abundance and expanded distribution of introduced blue catfi sh Ictalurus furcatus populations in the Chesapeake Bay watershed have raised regional management concerns. This study uses information from multiple surveys to examine expansion of blue catfi sh populations and document their role in tidal river communities. Originally stocked in the James, York, and Rappahannock R...

Fatty acid peroxides have been found in the atherosclerotic human aorta. Glavind found a correlation between the extent of the atherosclerotic changes and the content of lipid peroxides. These lipid peroxides are very toxic to the tissues. There are several compounds in the tissues to counteract the toxicity of peroxides in vivo, i.e. SH compounds, ascorbic acid, or tocopherol. · It may be infe...