About 150 researchers around the world convened at the Chateau Lake Louise on February 20-23, 2011 to present and discuss the latest research in human and animal imaging and spectroscopy at field strengths of 7 T or above (termed ultrahigh field) at the third ISMRM-sponsored high field workshop. The clear overall message from the workshop presentations and discussion is that ultrahigh field ima...

Introduction Using Diffusion Tensor Imaging (DTI) sequence provided by magnetic resonance imaging system, the diffusion properties of water can be quantified by measuring the diffusion anisotropy within each voxel [1]. Thus, one is able to track axons in white matter since their diffusivity is significantly higher than that of the rest of the tissue. The aim of this work is to use DTI to assess...

Acknowledgements. This paper summarises the results of updating and extending a previous study of Britain's relative productivity performance. Funding for this work was provided jointly by the Department of Trade and Industry, HM-Treasury and The Office for National Statistics, to whom we owe thanks. The research benefited from frequent meetings and detailed comments from representatives of the...

In the processing and analysis of diffusion tensor imaging (DTI) data, certain predefined morphological features of diffusion tensors are often represented as simplified scalar indices, termed diffusion anisotropy indices (DAIs). When comparing tensor morphologies across differing voxels of an image, or across corresponding voxels in different images, DAIs are mathematically and statistically m...

OBJECTIVE To provide an overview of diffusion tensor imaging (DTI) and its application to the study of white matter in the developing brain in both healthy and clinical samples. METHOD The development of DTI and its application to brain imaging of white matter tracts is discussed. Forty-eight studies using DTI to examine diffusion properties of the developing brain are reviewed in the context...

Introduction: The most common primary tumors of brain are gliomas and tumor grading is essential for designing proper treatment strategies. The gold standard choice to determine grade of glial tumor is biopsy which is an invasive method. The purpose of this study was to investigatethe role of fiber density index (FDi) by means of diffusion tensor imaging (DTI) (as a noninvasive method) in glial...

Image distortion caused by gradient eddy currents is a major problem in the use of diffusion tensor imaging (DTI), as using the uncorrected images for calculation of apparent diffusion coefficient (ADC) and diffusion anisotropy will result in areas of artificially increased anisotropy and ADC at the edge of the images, as well as decreased spatial resolution and accuracy in ADC computations ove...

Diffusion tensor imaging has been used extensively as a research tool to understand the structural changes associated with white matter pathology. Using water diffusion as the basis to construct anatomic details, diffusion tensor imaging offers the potential to identify structural and functional adaptations before gross anatomical changes, such as lesions and tumors, become apparent on conventi...

Apolipoprotein E epsilon4 is a major genetic risk factor for Alzheimer's disease, but the neurobiological basis for this risk is unknown. We used diffusion tensor imaging to measure diffusion anisotropy in the parahippocampal gyrus white matter in healthy elderly apolipoprotein E epsilon4 carriers and noncarriers. We also measured volumes of the lateral ventricles and temporal horns as proxies ...

The authors make a complete review of the potential clinical applications of traditional and novel magnetic resonance imaging (MRI) techniques in the evaluation of patients with Alzheimer's disease, including structural MRI, functional MRI, diffusion tension imaging and magnetization transfer imaging.