A 67 year-old woman presented with stable effort angina. A resting electrocardiogram was inconclusive. High-dose dipyridamole contrast-echocardiography shows normal left ventricular wall motion after 0.84mg/kg/6min dipyridamole. At rest a turbolent flow demonstrable by color aliasing, appeared in the territory of the left anterior descending coronary artery (LAD) during the diastolic phase.

Purpose To validate mitral valve annular velocities extracted in an automated fashion using an established algorithm for database guided landmark detection and temporal propagation based on inverse consistent non-rigid registration [1] in a normal population. To correlate the derived early diastolic myocardial peak-velocity measurements (e prime or e’) against phase contrast methods and to eval...

We report on a patient without heart disease who had pulsus paradoxus, associated with echocardiographic evidence of abnormal and exaggerated diastolic motion of interventricular septum. Both phenomena appeared at the peak of the inspiratory phase of respiration, and seemed to be produced from the same haemodynamic variations, of which the echocardiographic pattern appears to be a more sensitiv...

In an open, randomized, cross-over study the hypotensive action and side effects of clonidine-chlorthalidone and methyldopa-chlorthalidone combinations were compared. The diastolic morning blood pressure could be reduced to 95 mm. Hg or below in significantly more patients with clonidine than with methyldopa. Side effects, however, were more commonly encountered during the clonidine than during...

Conventional intracellular recordings from the bundle of His and right bundle branch of the canine heart demonstrated that the slope of diastolic depolarization is markedly depressed by superfusion with relatively small concentrations (4—8 jug/ml) of acetylcholine. As the cells become less automatic, take-off potential increases, rise time of phase 0 is reduced, action potential amplitude incre...

The influence of vasodilators in the natural history of mitral regurgitation is controversial. If, on the one hand, they may really interfere, on the other, they may mask left ventricular myocardial dysfunction. Three phases comprise the natural history of mitral regurgitation. In the first, increased atrial compliance and eccentric ventricular hypertrophy are observed in association with diast...

Preparations of right ventricular papillary muscle and false tendon (Purkinje fiber) were obtained from dog hearts, placed in a bath perfused with Tyrode solution, and observed both under control conditions and during exposure to lidocaine in concentrations from 1 x 10(-7) to 5 x 10(-4) mole/liter. Transmembrane voltages were recorded from both ventricular muscle (VM) and Purkinje fibers (PF) o...