Background: The number of patients suffering from diabetic ulcers has been increased in recent years and the current therapies have faced failure. This study aimed to investigate the effects of Wharton’s jelly stem cells (WJMSCs) on the diabetic wound in an animal mode. Methods: During this laboratory experimental study carried out in Skin and Stem Cells Research Center from March 2021 to Nove...

Cutaneous changes after local corticosteroid administration may include dermal atrophy, hyperpigmentation, alopecia, and hypopigmentation. Linear hypopigmentation and atrophy after intralesional injection of triamcinolone acetonide has been reported in the literature as a very rare side effect. A 30-year-old woman visited our dermatology department for a linear hypopigmented patch with atrophy ...

Diabetic rats in long-term display an augmented nociceptive response to thermal stimuli. Furthermore, hyperalgesia is one of the major symptoms of diabetic neuropathy in some patients. Considering the antidiabetic potential of medicinal plants chard, pepper, and tarragon, this study was undertaken to evaluate the possible analgesic effect of chard-, pepper-, and/or tarragon-mixed food intake in...

introduction: neuropathic pain is one of the common complications of diabetes mellitus which is caused by impairment in nerve conductivity. the role of flavonoid and polyphenol compounds in treatment of neuropathic pain has been revealed, and extract of onion contains significant amounts of these compounds. the aim of this study was to investigate the effect of alcoholic extract of onion on dia...

purpose: to evaluate pupil dilation with intracameral injection of preservative-free lidocaine 1% during phacoemulsification. methods: this interventional case series included 31 consecutive senile cataract patients scheduled for phacoemulsification and intraocular lens (iol) implantation. pupil dilation was achieved using intracameral preservative-free lidocaine 1% without any preoperative or ...

BACKGROUND Primary adhesive capsulitis is mainly characterized by spontaneous chronic shoulder pain and the gradual loss of shoulder motion. The main treatment for adhesive capsulitis is a trial of conservative therapies, including analgesia, exercise, physiotherapy, oral nonsteroidal anti-inflammation drugs, and intra-articular corticosteroid injections. Previously, it was reported that intra-...

Although the 1949 discovery of cortisone was a medical landmark, it is still unclear whether this widely used treatment benefi ts patients with tendon pain. In The Lancet today, Brooke Coombes and colleagues evaluate whether corticosteroid injection helps or harms patients with tendinopathies. This question is relevant not only for physicians, but also for other health professionals such as tho...