We present a double-helix point spread function (DH-PSF) based three-dimensional (3D) microscope with efficient photon collection using a phase mask fabricated by gray-level lithography. The system using the phase mask more than doubles the efficiency of current liquid crystal spatial light modulator implementations. We demonstrate the phase mask DH-PSF microscope for 3D photo-activation locali...

OBJECTIVE To report the first case of duloxetine hydrochloride (DH)-induced oral lichenoid drug reaction (OLDR). CLINICAL PRESENTATION AND INTERVENTION A 57-year-old male patient presented with painful ulcerative lesions on the bilateral buccal mucosa of 2-year duration. The patient was on multiple drug therapy for his systemic ailments. After thorough evaluation for possible medical ailments...

BACKGROUND Environmental enrichment (EE) exposure is known to influence the structural changes in the neuronal network of hippocampus. In the present study, we evaluated the effects of EE exposure on the streptozotocin (STZ)-induced diabetic and stressed rat hippocampus. METHODS Male albino rats of Wistar strain (4-5 weeks old) were grouped into normal control (NC), vehicle control (VC), diab...

OBJECTIVES (1) To systematically review peak vertical ground reaction force (PvGRF) during two-leg drop landing from specific drop height (DH), (2) to construct a mathematical model describing correlations between PvGRF and DH, and (3) to analyze the effects of some factors on the pooled PvGRF regardless of DH. METHODS A computerized bibliographical search was conducted to extract PvGRF data ...

Evidence for different physiological properties along the hippocampal longitudinal axis is emerging. Here, we examined the electrophysiological features of neurons at different dorso-ventral sites of the mouse CA1 hippocampal region. Cell position was defined with respect to longitudinal coordinates of each slice. We measured variations in neuronal excitability, subthreshold membrane properties...

1. Narod SA. Early-onset breast cancer: what do we know about the risk factors? A Countercurrents Series. Curr Oncol 2011;18:204–5. 2. Green ED, Guyer MS on behalf of National Human Genome Research Institute. Charting a course for genomic medicine from base pairs to bedside. Nature 2011;470:204–13. 3. Ruder WC, Lu T, Collins JJ. Synthetic biology moving into the clinic. Science 2011;333:1248–52...

Two often cited but frequently confused pictorial cues to perceived depth are height in the picture plane (HPP) and distance to the horizon (DH). We report two psychophysical experiments that disentangled their influence on perception of relative depth in pictures of the interior of a schematic room. Experiment 1 showed that when HPP and DH varied independently with both a ceiling and a floor p...

Dermatitis herpetiformis (DH), bullous pemphigoid (BP), and pemphigus vulgaris (PV) are autoimmune bullous skin conditions with eosinophilic and neutrophilic infiltrations. While cytokines are crucial for the affinity and activation of different leukocyte cells in the inflammation and blister formation, there are no studies concerning a role of IL-36. The goal of the study was to analyze whethe...

Doubled haploid (DH) populations, particularly those from subspecies crosses possessing the wide compatible gene S5n , are important germplasm resources for rice genetic studies and breeding, but their feature and potential have not been fully assessed and explored. In the present study, we produced a DH population from the hybrid of japonica 668B and wide compatible indica T23. Genotyping of t...

Effect of treatment of mice with cyclophosphamide (CY) on the delayed hypersensitivity (DH) response was investigated in C57BL/6 mice. DH to methylated human serum albumin (MHSA) could be enhanced with CY in young mice but not in aged ones. DH enhancement with CY appeared to be due to elimination of suppressor T cells involved in DH. Effector T cells were also sensitive to CY, the damaging effe...