Developmental neurotoxicity (DNT) refers to the toxic effects induced by various chemicals on brain during the early childhood period. As human brains are vulnerable during this period, various chemicals would have significant effects on brains during early childhood. Some toxicants have been confirmed to induce developmental toxic effects on CNS; however, most of agents cannot be identified wi...

Neural circuit optimization occurs through sensory activity-dependent mechanisms that refine synaptic connectivity and information processing during early-use developmental critical periods. Fragile X Mental Retardation Protein (FMRP), the gene product lost in Fragile X syndrome (FXS), acts as an activity sensor during critical period development, both as an RNA-binding translation regulator an...

how to cite this article: fayyazi a, kheizrian l, kheradmand z, damadi s, khajeh a. evaluation of the young children with neurodevelopmental disability: a prospective study at hamadan university of medical sciences clinics. iran j child neurol. 2013 winter; 7 (1):29-33.   objective developmental impairment is a common problem in children health that occurs in approximately 5–10% of the childhoo...

BACKGROUND Developmental disabilities have been reported in infants with persistent pulmonary hypertension of the newborn (PPHN) treated with inhaled nitric oxide (INO) or intravenous magnesium sulphate (MgSO(4)) and/or extracorporeal membrane oxygenation. This paper reports the rate of developmental disabilities at 2 years of age in a cohort of survivors of PPHN treated with INO, MgSO(4), or b...

Callosal connections form elaborate patterns that bear close association with striate and extrastriate visual areas. Although it is known that retinal input is required for normal callosal development, there is little information regarding the period during which the retina is critically needed and whether this period correlates with the same developmental stage across species. Here we review t...

how to cite this article: yaghini o, danesh f, mahmoudian t, beigi b. evaluation of developmental delay in infants who came in for 6th month vaccination in isfahan city health centers. iran j child neurol 2012;6(2): 29-32.   objective developmental delay is one of the most common causes of conferring the pediatric neurologist. the main part of neurological growth and development occur in the fi...

Infancy is a critical developmental period involving establishment of the neurological underpinnings of psychological, affective and relational functioning. The integration of findings from developmental and attachment theories and neurodevelopment has contributed to greater understanding of the significance of early relationships and the developmental impact of interactional disturbance. This ...