The pattern of feather buds in a tract is thought to result from the relative ratios between activator and inhibitor signals through a lateral inhibition process. We analyse the role of Drm/Gremlin, a BMPs antagonist expressed during feather pattern formation, in the dermal precursor, the dense dermis, the interbud dermis and in the posterior dermal condensation. We have altered the activity of...

A 76-year-old man presented with fever, and pain in his right ear. Physical examination revealed tender edematous, erythema, and a few vesicles of the right ear, along with facial involvement (Picture 1, 2). Laboratory examination showed neutrophilic leukocytosis. The next day, his left ear and face showed a tender light-colored erythema (Picture 3). After treatment with intravenous ceftriaxone...

To determine whether the factor(s) responsible for the conservation of epidermal specificities in adult guinea pigs and hamsters resides in the germinal layer of the epidermis or in the dermis, thin grafts of skin, possessing qualitatively distinct regional characteristics, were separated into their superficial epidermal and dermal components with the aid of trypsin. Dermis of one type was comb...