The antibacterial agent mupirocin (pseudomonic acid A) is used as a topical agent in the treatment of superficial infections by Gram-positive bacteria, particularly Staphylococcus aureus. However, we demonstrate here that the compound also inhibits the growth of a number of pathogenic fungi in vitro, including a range of dermatophytes and Pityrosporum spp. It inhibited the incorporation of amin...

This study was conducted to evaluate the effect of ethanolic, ethyl acetate and hexane extracts of Indian medicinal plants Azadirachta indica and Acalypha indica leaves against dermatophytes (60 isolates of Trichophyton rubrum, 22 isolates of Trichophyton mentagrophytes, 9 isolates of Microsporum gypseum and 9 isolates of Trichophyton tonsurans). Of the three extracts used the ethanolic and eth...

The present review deals with fungal keratinases including that of dermatophytes. Bacterial keratinases were also included. Temperature and substrate relationship keratinase production has also been discussed. Keratin degradation and industrial involvement of keratinase producing fungi is also reviewed.

According to the recent changes in classification of family Arthrodermataceae, it may already include 9 genera and 79 species. Dermatophytes associated with human animal infections belong Trichophyton, Microsporum Epidermophyton, whereas Arthroderma, Ctenomyces, Guarromyces, Lophophyton, Nannizzia Paraphyton are mainly represented by geophilic Since morphological physiological traits fungi cann...