A commercial optically stimulated luminescence (OSL) dosimetry system was investigated for in vivo dosimetry in radiation therapy. Dosimetric characteristics of InLight dot dosimeters and a microStar reader (Landauer Inc.) were tested in (60)Co beams. The reading uncertainty of a single dosimeter was 0.6%. The reproducibility of a set of dosimeters after a single irradiation was 1.6%, while in ...

NIST developed the alanine dosimetry system in the early 1990s to replace radiochromic dye film dosimeters. Later in the decade the alanine system was firmly established as a transfer service for high-dose radiation dosimetry and an integral part of the internal calibration scheme supporting these services. Over the course of the last decade, routine monitoring of the system revealed a small bu...

The influence of X-ray baggage scanning on electron spin resonance (ESR) dosimetry studies around the Semipalatinsk Nuclear Test Site (SNTS) has been examined at Incheon Airport in Korea, which is a transfer point of the routes from Kazakhstan to Japan. Utilized dosimeters are Japanese human tooth enamel for ESR and glass dosimeters. The difference between the estimated doses with the X-ray sca...

Although radioactive iodine imaging and therapy are one of the earliest applications of theranostics, there still remain a number of unresolved clinical questions as to the optimization of diagnostic techniques and dosimetry protocols. I-124 as a positron emission tomography (PET) radiotracer has the potential to improve the current clinical practice in the diagnosis and treatment of differenti...

PRESAGE is a radiochromic solid dosimeter which shows promising potential for 3D proton beam dosimetry. Since an idea dosimeter should be water-equivalent, total depth dose distributions in two PRESAGE formulations irradiated by a 62 MeV proton beam were compared with that in water using GEANT4 Monte Carlo simulations. The dose delivered by secondary particles was also calculated. Our results s...

Radiation dosimetry is used to quantify the dose delivered during radiation therapy by using ionization chambers with several correction factors. Knowledge of these factors is needed at well below the 1% level in order to maintain the overall uncertainty on the reference dosimetry near 1-2%. The small magnitude of the corrections renders measurements very difficult. Monte Carlo calculations are...

Absorbed dose distributions in 3D imparted by a single (90)Sr/(90)Y beta particle seed source of the type used for intravascular brachytherapy were investigated. A polymer gel dosimetry medium was used as a dosemeter and phantom, while a special high-resolution laser CT scanner with a spatial resolution of 100 microm in all dimensions was used to quantify the data. We have measured the radial d...

Radiographic film dosimetry provides fast, convenient 2-D dose distributions, but is challenged by the dependence of film response on scatter conditions (i.e., energy dependence). Verification of delivered dose in the surface buildup region is important for intensity modulated radiation therapy (IMRT) when volumes of interest encroach on these regions (e.g., head/neck, breast). The current work...

Radionuclide therapy extends the usefulness of radiation from localized disease of multifocal disease by combining radionuclides with disease-seeking drugs, such as antibodies or custom-designed synthetic agents. Like conventional radiotherapy, the effectiveness of targeted radionuclides is ultimately limited by the amount of undesired radiation given to a critical, dose-limiting normal tissue,...

introduction: radioiodine therapy is an effective method for treating thyroid cancer carcinoma, but it has some affects on normal tissues, hence dosimetry of vital organs are important to weigh the risks and benefits of this method. the aim of this study is to measure the absorbed doses of important organs by mcnp (monte carlo n particle) simulation and comparing the results of different method...