RESUMEN Los retos del sector turístico después de la pandemia Covid-19 son monumentales. Recobrar confianza los turistas, hoteleros, agentes viajes y garantizar operación toda industria parece una empresa imposible en el corto plazo. A pesar ello, contingencia sanitaria ha traído un acelerador procesos digitalización comercio electrónico. Uno portales clave es TripAdvisor. El objetivo este artí...

Organizations are evolving from the bureaucratic form based upon hierarchy to the new-form or radix organization that has the value chain as its relatively fluid foundation. This article explores the relationship between the radix organization and leadership, viewed through an organization-environment coevolution framework. It explicates the changes in the leader’s role-sets and relationships b...

W hile working in Uganda, a physician by the name of Denison Parson Burkitt first described the tumor that now carries his name. In 1957, Dr. Burkitt, along with his colleagues, examined a child with what appeared to be swelling along the jaw. After observing a second child with the same clinical presentation, his curiosity prompted him to study hospital records for similar cases. He found that...

Genome sizes and mutation rates covary across all domains of life. In unicellular organisms and DNA viruses, they show an inverse relationship known as Drake’s rule. However, it is still unclear whether a similar relationship exists between genome sizes and mutation rates in RNA genomes. Coronaviruses, the RNA viruses with the largest genomes ( 30 kb), encode a proofreading 39 exonuclease that ...

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Is early orthodontic treatment indicated for anterior open bite malocclusions? Is the stability of open bite treatment a significant clinical problem? To answer these questions, I would like to define open bite as the lack of overlap of the anterior teeth in centric occlusion. Overlap pertains to the incisal edges as viewed from the anterior; the mandibular incisors do not contact any opposing ...

Based on the probabilistic reformulation of principal component analysis (PCA), we consider the problem of determining the number of principal components as a model selection problem. We present a hierarchical model for probabilistic PCA and construct a Bayesian inference method for this model using reversible jump Markov chain Monte Carlo (MCMC). By regarding each principal component as a poin...

The aryl hydrocarbon receptor (AHR) is a ligand-activated member of the bHLH-PAS family of transcription factors. Members of this family include HIF1a, EPAS, and SIM, which are involved in hypoxia and nervous system development. Another member of this family, aryl hydrocarbon nuclear translocator (ARNT), is the dimerization partner for the AHR. The AHR is often classified as a sensor of a wide ...

THE VERY ESSENCE OF MAMMALS as a taxonomic class is based on the mammary gland and the ability to provide milk as a total and sole nutritional source at the start of post-partum life. However, much remains to be learned regarding epithelial cellular mechanisms that account for milk composition and volume. In part, this lack of knowledge may reflect the complex interplay of hormones that contrib...