BACKGROUND Helicobacter pylori infection treatment was found not to reduce the prevalence of iron deficiency or anemia among Alaska Native children at 14 months after treatment initiation. We hypothesized that 14 months was to early to resolve H. pylori-induced gastric damage. Consequently, we conducted a 40-month follow-up. METHODS We enrolled 219 children 7-11 years old who had H. pylori in...

Using varied study designs (none of which can confirm causality), investigators assessed the health impact wheat flour fortification after it was implemented at large scale in countries. Folic acid most studied nutrient and outcomes were neural tube defects, cancer, folate status, deficiency, anemia, iron hemoglobin iron-deficiency anemia (IDA). For all these except IDA, majority studies showed...

An increase in the frequency of blood donation among the donor population is liable to result in excessive iron loss and development of iron deficiency anemia. In the majority of blood banks, hemoglobin and/or hematocrit measurements are used as screening tests for the ability to donate blood even though iron stores may be depleted in donors with hemoglobin values above the arbitrarily defi...

Sheehan’s syndrome (SS) or pituitary necrosis of the postpartum is a rare pathology and difficult to diagnose that can be life-threatening [1]. Microcytic anemia frequently associated with iron deficiency, sideroblastic anemia, inflammatory thalassemia [2] but rarely SS.

We evaluated the use of transferrin receptor (TfR) in serum as an index of iron deficiency in 19 patients diagnosed as having iron-deficiency anemia, in 17 patients with anemia of chronic disease, and in a control group of 19 nonanemic patients who underwent elective ocular or nasopharyngeal surgery. The assessment of iron status of the anemic patients was based on the presence of stainable iro...

Inflammatory disease as well as iron deficiency may play an important role in the cause of anemia in the United States. We evaluated the relationships between Fe deficiency, inflammatory disease, and anemia using data from of the First National Health and Nutritional Examination Survey (NHANES I). Fe nutrition index was based on the ratio of serum Fe to Fe-binding capacity (Fe:TIBC) and inflamm...

BACKGROUND Although iron deficiency is considered to be the main cause of anemia in children worldwide, other contributors to childhood anemia remain little studied in developing countries. We estimated the relative contributions of different factors to anemia in a population-based, cross-sectional survey. METHODOLOGY We obtained venous blood samples from 1111 children aged 6 months to 10 yea...

B12 deficiency is the leading cause of megaloblastic anemia, and although more common in the elderly, can occur at any age. Clinical disease caused by B12 deficiency usually connotes severe deficiency, resulting from a failure of the gastric or ileal phase of physiological B12 absorption, best exemplified by the autoimmune disease pernicious anemia. There are many other causes of B12 deficiency...