Sepsis is a syndrome consisting of physiological, pathological and biochemical anomalies caused by infectious agents. It causes clinical organ dysfunction, which identified an acute increase in the Sequential (sepsis-related) Organ Failure Assessment (SOFA) score two or more points. SOFA three components that can be easily used at bedside to track status patient while on admission, these are al...

Significance Sepsis is a condition wherein microbial infection leads to life-threatening systemic hyperactivation of innate immunity. Blood pH normally maintained tightly between 7.35 and 7.45, lactic acidosis with <7.3 indicates poor prognosis in sepsis, also associated low zinc levels. Release HMGB1 from activated and/or necrotic tissues plays pivotal role triggering the proinflammatory ca...

Introduction: Neonatal sepsis, and Neonatal septiemia are terms that have been used to describe the systemic response to infection in newborn infants. Sepsis can affect neonatal metabolism and the level of blood sugar. The aim of this study is to assess the prevalance of “Hypoglycemia” in neonates with primary diagnosis of sepsis in neonatal ward and NICU of khorrammabad pediatric hospital on...

Background & aim: Studies have shown that puerperal sepsis is a major cause of maternal morbidity and the second cause of maternal mortality in the developing world. This study aimed to determine the incidence and management of puerperal sepsis among the women of reproductive age (i.e., 15-49 years) attending to two hospitals in Nandi County, Kenya. Methods: This descriptive, cross-sectional st...

A deep understanding of the pathogenesis is key point in formation diagnostic strategies and treatment tactics for patients with various diseases. In this paper, thorough analysis microscopic processes that occur bodies purulent-septic diseases was carried out. The pathogenetic concept model purulent-inflammatory sepsis proposed presented. It based on fact accompanied by endogenous intoxication...

Neonatal sepsis (NS) is one of the major causes morbidity and mortality in neonatal age. NS classified according to time symptoms Early-Onset Sepsis (EOS) Late-OnsSepsis (LOS). In new studies, neutrophil/lymphocyte ratio (NLR) platelet/lymphocyte have been used determining existence severity sepsis. This a sign inflammation, it can be foreseeing septicemia.

T he natural history of serious burns is characterized by burn shock, which is usually lethal to those with large burns during the first few postinjury days, burn wound sepsis, which commonly kills those who survive burn shock during the first few postinjury weeks, and postburn deformity in those who survive to heal their wounds by contraction and epithelialization. Each of these issues has bee...