Diabetes mellitus is metabolic syndrome that causes disability, early death, and many other complications. Currently insulin and many synthetic drugs are used in diabetes treatment. However, these pharmaceutical drugs are too expensive particularly for sub-Saharan population in addition to their undesirable side effects. The present study was aimed to evaluate antidiabetic effect and toxicity l...

In this study the use of plants for medicinal purpose used locally in the treatment of various diseases and we examined for their antioxidant activity. Therefore, the present investigation is part of continuing programme related to the biochemical screening of local plants used in Ancient Indian Medicine, Ayurveda, Siddha and Yunani. An Aqueous root extract of Withania Somnifera (L.) Dunal (Ash...

Leaves of Murraya koenigii (Linn.) Spreng. (Curry patta) are reported to possess antidiabetic, antimicrobial, cytotoxic and anti-inflammatory activity. In the present study immunomodulatory potential of aqueous extract of its leaves on specific (humoral and cell mediated) and non specific (macrophage) immunity in mice was investigated. Oral administration of the aqueous extract of leaves at the...

BACKGROUND Traditionally GS is used to treat diabetes mellitus. Drug-herb interaction of GS via cytochrome P450 enzyme system by substrate cocktail method using HLM has not been reported. OBJECTIVE To evaluate the in-vitro modulatory effects of GS extracts (aqueous, methanol, ethyl acetate, chloroform and n-hexane) and deacylgymnemic acid (DGA) on human CYP1A2, 2C8, 2C9, 2D6 and 3A4 activitie...

In Iranian traditional medicine, olive has been reported to have analgesic and anti-inflamatory effects. In the present study the anti-nociceptive and anti-inflamatory effects of olive fruit has been studied. In this study the methanolic and aqueous extract of the fruit with HER (Herbal to Extract Ratio) of 4.96% and 4.84% has been used and analgesic effect of this extract has been compared wit...

P. niruri has been reported to possess antidiabetic and kidney protective effects. In the present study, the phytochemical constituents and in vitro antioxidant activity of P. niruri leaf aqueous extract were investigated together with its effect on oxidative stress and antioxidant enzymes levels in diabetic rat kidney. Results. Treatment of diabetic male rats with P. niruri leaf aqueous extrac...

Article history: Received on: 05/02/2014 Revised on: 26/02/2014 Accepted on: 19/03/2014 Available online: 27/05/2014 The present study was aimed to assess the plants antimicrobial effects such as Tamarisk, March, acetone and mango kernel. The aqueous and ethanol extract of the plants and also its smoke was prepared in concentrations of 50 and 25 mg/mL. The bacteria Staphylococcus aureus, Strept...

We have investigated effect of Moringa oleifera leaf and fruit extracts on markers of oxidative stress, its toxicity evaluation, and correlation with antioxidant properties using in vitro and in vitro assays. The aqueous extract of leaf was able to increase the GSH and reduce MDA level in a concentration-dependent manner. The ethanolic extract of fruit showed highest phenolic content, strong re...

background and objective: in this research, the effect of chronic dietary soybean aqueous extract on aortic reactivity of streptozotocin (stz)-diabetic rats was investigated. materials and methods: stz-diabetic rats were treated with soybean aqueous extract for two months after diabetes induction. contractile reactivity to kcl and phenylephrine (pe) and relaxation response to acetylcholine (ach...