Four strains of Aedes aegypti (L.), one from Cuba and three from Venezuela, were bioassayed for susceptibility to eight insecticides, including the organophosphates, temephos, malathion, fenthion, pirimiphos methyl, and chlorpyrifos, and the pyrethroids, deltamethrin, lambda cyhalothrin and cypermethrin, S, S, S,-tributyl phosphorotrithioate and piperonyl butoxide were used as synergists to ass...

Carboxylesterases hydrolyze a large array of endogenous and exogenous ester-containing compounds, including pyrethroid insecticides. Herein, we report the specific activities and kinetic parameters of human carboxylesterase (hCE)-1 and hCE-2 using authentic pyrethroids and pyrethroid-like, fluorescent surrogates. Both hCE-1 and hCE-2 hydrolyzed type I and II pyrethroids with strong stereoselect...

Cypermethrin and beta-cyfluthrin are two most widely used multipurpose pyrethroids. After determining their oral LD50 (416.98 mg kg-1 and 354.8 mg kg-1 body weight, respectively), we assessed their hepatotoxicity in Wistar rats following acute (0.1 LD50 for 1 day) and sub-acute (0.1 LD50 for 7, 14, 21 or 28 days) poisoning. The assessment was based on hepatic marker enzymes AST, ALT, LDH, ALP, ...

Pesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. These compounds are absorbed by inhalation, ingestion, and dermal contact. Their bioavailability in the individuals can lead to a variety of metabolic and systemic dysfunctions, and even outright disease states. Therefore, the tremendous usage of pesticides has promoted toxicological stud...

In this study, an analysis of pesticide residues was performed using a gas chromatography/ electron impact mass spectrometer (GC/EI-MS) to qualitatively assess and characterize in khat leaves sampled from selected agricultural farms Meru County, Kenya. A solid-phase microextraction (SPME) procedure followed by GC/EI-MS led the detection identification six compounds sample-ion chromatograms. The...

Species differences in the intrinsic clearance (CL(int)) and the enzymes involved in the metabolism of pyrethroid pesticides were examined in rat and human hepatic microsomes. The pyrethroids bifenthrin, S-bioallethrin, bioresmethrin, beta-cyfluthrin, cypermethrin, cis-permethrin, and trans-permethrin were incubated in rat and human hepatic microsomes in the presence or absence of NADPH. Metabo...

The study was undertaken to determine the purity level of eleven selected pesticides collected from different locations Bangladesh. In this study, Gas Chromatography coupled with Flame Ionization Detector (FID) and Electron Captured (ECD) used acephate, diazinon, dimethoate, chlorpyrifos, quinalphos, malathion, fenitrothion cypermethrin, fenvalerate. High Performance Liquid (HPLC 20A Prominence...

Abstract The current study was designed to assess the ameliorative and potential adverse effects of date fruit extracts (Phoenix dactylifera) on cypermethrin-induced male infertility. conducted in two phases using adult Wistar rats (n = 42). first phase a single oral dose toxicity ascertain suitability extract cypermethrin at 250 mg/kg 60 mg/kg, respectively. second assessed fruits At terminati...

The toxicity of cypermethrin (a pesticide) on fingerlings African catfish, Clarias gariepinus was investigate with emphasis histopathological effects. juvenile were exposed to 0, 1.0, 2.0, 3.0, 4.0 and 5.0ppb under experimental condition. growth, nutrient utilization feed parameters (Weight gain, Average Daily Weight Gain, Percentage Gain , Specific Growth Rate Feed Intake ,Feed Conversion Rati...