The volatile composition of fruit from four Citrus varieties (Powell Navel orange, Clemenules mandarine, and Fortune mandarine and Chandler pummelo) covering four different species has been studied. Over one hundred compounds were profiled after HS-SPME-GC-MS analysis, including 27 esters, 23 aldehydes, 21 alcohols, 13 monoterpene hydrocarbons, 10 ketones, 5 sesquiterpene hydrocarbons, 4 monote...

gem-dihydroperoxides as nearly stable peroxidic derivatives of aldehydes and ketones are known important intermediates in synthesis of anti-malaria drugs. also, because containing high concentration of peroxidic oxygen, recently, some of these compounds have been used as solid, efficient and powerful oxidants in many oxidation organic reactions. generally, these compounds are synthesized via pe...

In this paper we report the synthesis of new compounds based on the pyrazole and isoxazole framework fused to a cycloalkene unit, and bearing as a substituent the 1-piperidinyl group as new examples of potential antipsychotic molecules. The general synthesis involves the acylation of a chloro-substituted cyclic ketone with a 1-substituted piperidine-4-carboxylate derivative, followed by heteroc...

The industrially–viable aerobic α–alkylation of cyclic and acyclic ketones with allyl alkyl alkenes in the presence catalytic amounts Mn2+, under homo– heterogeneous conditions, is achieved here. substitution organic peroxides by Mn2+ either as a simple soluble salt or supported zeolites, air, generates in–situ peracid radicals circumvents aggressiveness current industrial protocols, to pave wa...

Ketones have previously shown beneficial effects in models of neurodegenerative disorders, particularly against associated mitochondrial dysfunction and cognitive impairment. However, evidence of a synaptic protective effect of ketones remains lacking. We tested the effects of ketones on synaptic impairment induced by mitochondrial respiratory complex (MRC) inhibitors using electrophysiological...

Functionalized chiral ketones, such as a-amino ketones, bnitro ketones, and their derivatives, are prevalent building blocks and ubiquitous subunits present in natural products and pharmaceutical lead compunds. The synthesis of chiral ketones can be achieved through direct a substitution. For example, the synthesis of a-amino ketones has been developed by Jørgensen and co-workers using an elega...

The Mo(CO)6-mediated photoinduced ring-opening reactions of adamantane isoxazolines involve novel rearrangement that provide enaminoketones as major products and b-hydroxy ketones as minor ones; in contrast, only b-hydroxy ketones and a,b-unsaturated ketones were obtained under thermal condition. 2006 Elsevier Ltd. All rights reserved. Table 1. Synthesis of substituted adamantane-isoxazolines 1a–d