نتایج جستجو برای: cyc lophosphamide
تعداد نتایج: 1096 فیلتر نتایج به سال:
Monosymmetry evolved several times independently during flower evolution. In snapdragon (Antirrhinum majus), a key gene for monosymmetry is CYCLOIDEA (CYC), which belongs to the class II TCP gene family encoding transcriptional activators. We address the questions of the evolutionary history of this gene family and of possible recruitment of genes homologous to CYC in floral development and sym...
RATIONALE The Scleroderma Lung Study enrolled 158 patients with scleroderma-related interstitial lung disease in a placebo-controlled trial of oral cyclophosphamide (CYC). Although treatment-related benefits in pulmonary function, skin scores, and patient-centered outcomes were demonstrated after 1 year of therapy, the duration of benefit beyond 1 year was unclear. OBJECTIVES A second year of...
We are interested in building and maintaining semantic nets in general, and hierarchical semantic nets in particular. In [Mili, 1988], we developed a model of hierarchical semantic nets that generalizes taxonomic models by replacing the concept of property inheritance by a more general behavior of properties that we called regularity [Mili & Rada, 1990a]. We are also interested in the generatio...
California Youth Connection (CYC) is the state's only non-profi t youth advocacy and leadership organization dedicated to giving current and former foster youth the skills necessary to engage directly with policymakers to improve the foster care system. Formed out of the fundamental belief that policymakers can benefi t from the input of those who have experienced fi rst-hand the impact of chil...
OBJECTIVES To determine whether there are racial/ethnic differences in the willingness of SLE patients to receive CYC or participate in clinical trials, and whether demographic, psychosocial and clinical characteristics contribute to these differences. METHODS Data from 120 African-American and 62 white lupus patients were evaluated. Structured telephone interviews were conducted to determine...
Circadian clocks in eukaryotes keep time via cell-autonomous transcriptional feedback loops. A well-characterized example of such a transcriptional feedback loop is in Drosophila, where CLOCK-CYCLE (CLK-CYC) complexes activate transcription of period (per) and timeless (tim) genes, rising levels of PER-TIM complexes feed-back to repress CLK-CYC activity, and degradation of PER and TIM permits t...
Deleterious interactions among genes cause reductions in fitness of interpopulation hybrids (hybrid breakdown). Identifying genes involved in hybrid breakdown has proven difficult, and few studies have addressed the molecular basis of this widespread phenomenon. Because proper function of the mitochondrial electron transport system (ETS) requires a coadapted set of nuclear and mitochondrial gen...
Phosphoglyceride-linked enterobacterial common antigen (ECA(PG)) is a cell surface glycolipid that is synthesized by all gram-negative enteric bacteria. The carbohydrate portion of ECA(PG) consists of linear heteropolysaccharide chains comprised of the trisaccharide repeat unit Fuc4NAc-ManNAcA-GlcNAc, where Fuc4NAc is 4-acetamido-4,6-dideoxy-D-galactose, ManNAcA is N-acetyl-D-mannosaminuronic a...
PURPOSE To determine whether taurine exerts a protective effect on retinal pigment epithelium (RPE) cells exposed to a cytotoxic agent, cytochrome C (cyC), shown previously to induce apoptosis and produce cell death in electrically coupled neighboring cells. METHODS Monolayer cultures of confluent human RPE (ARPE-19) cells, which express gap-junctional proteins, were incubated in culture medi...
Cyc is a monumental but controversial research eeort for codifying the human consensus knowledge initiated by Doug Lenat in 1984. The human consensus knowledge is meant to be the background knowledge that a human is assumed to possess in order to understand, for example, newspaper articles or encyclopedia entries. The methodology chosen is to enter this knowledge explicitly in a large knowledge...
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