Wind-up is described traditionally as a frequency dependent increase in the excitability of spinal cord neurons, evoked by electrical stimulation of afferent C-fibers. Different kinds of wind-up have been reported, but wind-up of Abeta fibers in hyperalgesic states has gained little attention. In this paper, we present a cybernetic view on Abeta fiber wind-up and consider the involved molecular...

ion linguistic objects play the most essential part. The principal thing here is construction not abstraction. Abstraction without construction simply leads to loss of meaning, to concepts such as “something” and “some.” [1] Quoted from Novoe v lingvistike (New Developments in Linguistics). No 1. Moscow, 1960. [Original Whorf article in Language, Culture, and Personality, Menasha. Wisconsin, 19...

In 1969, Gordon Pask published a paper that explicitly proposed a vital connection between cybernetics and architecture. “The Architectural Relevance of Cybernetics” (Pask, 1969) was one outcome of an extraordinary series of debates and presentations centred around the theme of limits to science presented at the Architectural Association School of Architecture (AA) in London. The proceedings we...

We take the position that Cybernetics offers a theoretical basis for the development of components, component frameworks, and component framework frameworks. Although not recognized as such, Cybernetic principles are currently used in successful software. A goal in proposing Cybernetics for component design is to permit the development of organic software systems to meet increasingly complex ap...

The interaction between real and virtual spaces can be reconceptualized by mobilizing the notion of cybernetic space to signify the relationship between spaces, culture and identity in the synthetic space we tend to live in. The new metaphor can allow for a holistic examination of the Internet in popular culture.

A new paper in Science reveals how repetitive stimulation can identify and help to repair fragilities within a signaling network, while using linear mathematical models inspired by engineering, thereby suggesting how cybernetic methods can be integrated into systems and synthetic biology.