INTRODUCTION Mycosis fungoides is a kind of malignant lymphoma arising from T cells, but primarily occurs in skin, and it is the most common type of cutaneous lymphoma. Mycosis fungoides (MF) is a rare non-Hodgkin lymphoma but the most common type of primary cutaneous T-cell lymphomas. Because of unknown etiology and mechanism, and lack of typical clinical and histophysiological manifestations,...

The characteristic histopathological feature of mycosis fungoides (MF) and adult T-cell leukemia/lymphoma (ATLL) is epidermotropism. To identify the mechanism for epidermotropism of lymphoma cells, total RNAs were obtained from skin biopsies of epidermis and dermis of MF and ATLL patients by means of laser capture microdissection, and used for subsequent complementary DNA (cDNA) microarray expe...

Primary cutaneous follicle center lymphoma is an indolent primary cutaneous B-cell lymphoma originating from the follicle center cells, composed of a combination of centrocytes (small and large cleaved cells) and centroblasts (large noncleaved cells) with a follicular, follicular/diffuse, or diffuse growth pattern. Lesions are mostly located on the head, neck and trunk. A case is presented of a...

Gastric adenocarcinoma developing concomitantly with a lymphoma is rare. Furthermore, B-cell lymphoma, originating from lymph nodes, with eosinophilia is extremely rare. We report here a case with a synchronous diffuse large B-cell lymphoma (DLBCL) and an early adenocarcinoma of the stomach. In addition, this case seemed to be associated with paraneoplastic cutaneous vasculitis caused by hypere...

One newly recognized form of T-cell lymphoma is breast implant-associated anaplastic large cell lymphoma (biALCL), which appears in close proximity to breast implants. The number of reported cases of biALCL is increasing and warrants careful attention by clinicians to more effectively diagnose and treat affected individuals. As pertinent to dermatologists, the objective of this paper is to pres...

Mantle cell lymphoma is a type of non-Hodgkin lymphoma that affects extranodal areas, especially, bone narrow, digestive tract and Waldeyer ring. Here we report a case of mantle cell lymphoma IV Ann Arbor stage with cutaneous lesions on nasal dorsum and glans penis as the first manifestations. Skin involvement is a very rare manifestation and less than 20 cases have been reported in the literat...

Part 3, chapter 16. In: An illustrated guide to skin lymphoma. 2nd edn. Oxford: Blackwell Publishing Ltd; 2004, p. 133-137. 3. PetrellaT, Bagot M, Willemze R, Beylol-Barry M. Vergier B. Delaunay M, et a!. Blastic NK-cell lymphomas (agranular CD4+ CD56+ hematodermic neoplasms). Am J Clin Pathol 2005;123:662-675. 4. Adachi M, Maeda K, Takekawa M. Hinoda Y. Imai K, Sugiyama S. et al. High expressi...

Sir, The presence of a granulomatous pattern has rarely been described in cutaneous lymphomas, mycosis fungoides (MF) being the variant more frequently reported (1 – 4). The aetiology of granulomatous reactions remains unclear and its prognostic value is still disputed, although a favourable influence on outcome has been hypothesized (5). We report here the case of an 87-year-old man with nodal...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. Approximately 50% of a...

Primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT), is a rare and aggressive variant of extranodal lymphoma. We report the case 64-year-old woman with unilateral lymphedema lower limb as first only symptom PCDLBCL-LT for six months. Violaceous nodules were second they progressively developed on edematous calf. Initially, diagnosed warty overgrowths, which are common skin cha...