Adrenal masses that are found incidentally should be evaluated with both imaging and hormonal studies. The attenuation coefficient on noncontrast computed tomography (CT), expressed in Hounsfield units (HU), is better than tumor size in differentiating adrenal adenomas and hyperplastic lesions from nonadenomas. All patients should undergo hormonal evaluation for Cushing syndrome and pheochromoc...

of three-dimensional features Chad M. Huard Department of Electrical Engineering and Computer Science, University of Michigan, 1301 Beal Ave., Ann Arbor, Michigan 48109-2122 Yiting Zhang, Saravanapriyan Sriraman, and Alex Paterson Lam Research Corp., 4650 Cushing Parkway, Fremont, California 94538 Mark J. Kushner Department of Electrical Engineering and Computer Science, University of Michigan,...

Cushing's syndrome is a state of cortisol excess, possibly from a tumor in the pituitary gland, the adrenal gland, or an ectopic nonpituitary ACTH-secreting source. The first form, pituitary in origin, was originally described by Harvey Cushing, MD, and was labeled as Cushing's disease. Long-term therapy with glucocorticoids also can lead to iatrogenic Cushing's syndrome.

Rapid onset obesity, hypoventilation, hypothalamic, autonomic and thermal dysregulation, and neural tumours constitute a rare but distinct clinical syndrome (ROHHADNET) [1,2]. This commonly presents with obesity, but rapidly progresses to cardio-respiratory arrest and death in childhood if inappropriately managed. Rapid onset obesity, hypoventilation, hypothalamic, autonomic and thermal dysregu...

BACKGROUND AND PURPOSE Arginine vasopressin V(1) receptors have been suggested to be involved in the pathophysiology of acute brain injury. Therefore, we aimed to determine the role of arginine vasopressin V(1) receptors after experimental subarachnoid hemorrhage (SAH). METHODS Sprague-Dawley rats subjected to SAH by endovascular puncture received either vehicle or a V(1) receptor antagonist ...

La fréquence des thromboses veineuses profondes au cours du syndrome de Cushing varie de 7 à 25%. Elles sont secondaires à des mécanismes multiples : élévation des taux des facteurs VIII, IX et de Von Willebrand, une réduction du TCA et une augmentation du TP. Nous rapportons l'observation d'une thrombose de la veine porte dont l'exploration étiologique a conduit au diagnostic du syndrome de Cu...

BACKGROUND Steroid cell tumors of ovary account for less than 0.1% of all ovarian tumors and these tumours may present at any age in association with interesting presentations related to hormonal activities. The subtype, not otherwise specified (NOS), is associated with androgenic changes in 56-77% and Cushing syndrome in 6-10%. Due to the rarity of available data regarding these tumors, little...

PURPOSE To document the accuracy of CT and MR of the sella turcica for detecting adrenocorticotropic hormone-secreting adenomas in Cushing disease. METHODS The radiologic findings of the sella turcica prior to transsphenoidal surgery are reviewed in 141 patients who had biochemical evidence of pituitary-dependent Cushing disease. Axial thin-collimation CT scans with sagittal and coronal refor...