The paper demonstrates the correlation between the chemical composition of steel grades and the hardness as well as the formability of laser welds generated with modern automotive high strength steel grades. At the very low heat input of industrial laser welding and the resulting extremely high cooling rate, the weld hardness is fully controlled by the carbon content of the base materials and n...

PURPOSE To quantitatively evaluate the change in the optic disc topographic parameters associated with reduction in the intraocular pressure (IOP) after trabeculectomy in adult patients with glaucoma. METHODS A series of 22 patients (mean age: 45.7+/-15.1 years) with several types of glaucoma were examined for various parameters of optic disc before and after trabeculectomy. Cup area, cup-to-...

BACKGROUND Cancer of unknown primary (CUP) accounts for approximately 3% of all malignancies. Avoiding immune destruction is a major cancer characteristic and therapies aimed at immune checkpoint blockade are in use for several specific cancer types. A comprehensive survey of predictive biomarkers to immune checkpoint blockade in CUP were explored in this study. METHODS About 389 cases of CUP...

The stability of cementless acetabular cups depends on a close fit between the components and reamed acetabular cavities to promote bone ingrowth. Cup performance and stability are affected by both design and environmental (patient-dependent and surgical) factors. This study used a statistically based metamodel to determine the relative influences of design and environmental factors on acetabul...

Glaucoma is a chronic eye disease that leads to blindness. This disease cannot be cured but we can detect the disease in time. Current tests using intraocular pressure (IOP) measurement are not sensitive enough for population based glaucoma screening. Optic nerve head assessment in retinal fundus images is more promising and superior than current methods. This paper proposes segmentation of opt...

Cancer of unknown primary sites (CUP) is a compilation of various malignant entities--the majority of which behave aggressively and carry poor prognosis. CUP is classified into two different clinicopathological groups: the unfavourable (poor-prognosis) and the favourable (good-prognosis) group. Patients with favourable subsets are treated relevant to the hidden primary tumour chemotherapy regim...

Glaucoma is a chronic eye disease that leads to vision loss. As it cannot be cured, detecting the disease in time is important. This research proposes optic disc and optic cup segmentation using superpixel classification for glaucoma screening. It uses the 2D fundus images. In optic disc segmentation, clustering algorithms are used to classify each superpixel as disc or nondisc. For optic cup s...

BACKGROUND There are multiple revision implant systems currently available for socket revision in revision total hip arthroplasty. Up until now, not all of these systems have been followed up with regards to their long-term use as a revision implantation.For the first time, this study presents the hemispherical porous-coated socket Plasmacup SC, produced by Aesculap, Tuttlingen, Germany, and th...

Captive-born male and female squirrel monkeys spontaneously 'invented' a cup tool use technique to Contain (i.e., hold and control) food they reduced into fragments for consumption and to Contain water collected from a valve to drink. Food cup use was observed more frequently than water cup use. Observations indicate that 68% (n = 39/57) of monkeys in this population used a cup (a plastic slip ...

BACKGROUND Medialization of the cup with a respective increase in femoral offset has been proposed in THA to increase abductor moment arms. Insofar as there are potential disadvantages to cup medialization, it is important to ascertain whether the purported biomechanical benefits of cup medialization are large enough to warrant the downsides; to date, studies regarding this question have disagr...