نتایج جستجو برای: cumulative index ipi and mcd
تعداد نتایج: 16869322 فیلتر نتایج به سال:
BACKGROUND We investigated factors that influence outcomes in diffuse large B-cell lymphoma (DLBCL) patients treated with rituximab combined with the CHOP regimen (R-CHOP) followed by upfront autologous stem cell transplantation (Auto-SCT). METHODS We retrospectively evaluated survival differences between subgroups based on the age-adjusted International Prognostic Index (aaIPI) and revised-I...
Introduction: The serum immunoglobulin free light chain (FLC) assay quantities of free kappa (κ) and lambda (λ) light chains. This assay has prognostic value in plasma cell proliferative disorders. There are limited data on serum FLC in B-cell malignancies. Objectives: The aim of this study was to compare the known prognostic factors in non-Hodgkin's lymphoma of the type B-cell and Hodgkin dise...
Previous studies with mast cell degranulating (MCD) peptide have shown that peptide [Ala]MCD 8 was an inhibitor of IgE binding to mast cell receptors. In an attempt to produce increased inhibition, analogs were synthesized that maintained the alanine residue in position 12 in the MCD peptide sequence and were further modified at both termini. Analogs modified at the C-terminus were [Ala,desLys]...
In this work, Municipal Corporation of Delhi (MCD) existing information sharing capabilities are analyzed to improve overall business performance to make MCD more competitive organization to face global challenges. MCD official are asked to provide their responses through questionnaire about their perceptions regarding various aspects of information sharing potential in using software applicati...
The pathogenesis of Epstein-Barr virus-positive (EBV+) mature T-cell and natural killer (NK)-cell neoplasms is challenging to understand. The clinical features are diverse, with no typical manifestation. Therefore, it is important to analyze the association of the clinical characteristics and prognoses of patients with various factors associated with EBV+ T/NK-cell neoplasms, particularly extra...
UNLABELLED Inhibition of malonyl-coenzyme A decarboxylase (MCD) shifts metabolism from fatty acid towards glucose oxidation, which has therapeutic potential for obesity and myocardial ischemic injury. However, ~40% of patients with MCD deficiency are diagnosed with cardiomyopathy during infancy. AIM To clarify the link between MCD deficiency and cardiac dysfunction in early life and to determ...
As a primary sink of pollutants, urban soil heavy metal pollution and its influence on residents ecosystems has been becoming one the most important environmental problems. In present study, four indices, Geoaccumulation index (Igeo), improved Nemerow (IMN), degree contamination (mCd), security (CSI), as well potential ecological risk (RI), were used to evaluate individual or integrated for sam...
UNLABELLED The physiological course of pregnancy is closely related to adequate development of the placenta. Shallow invasion of trophoblast as well as decreased development of the placental vascular network are both common features of preeclampsia. To better understand the proangiogenic features of mast cells, in this study we aim to identify the potential relationship between the distribution...
Treatment with rituximab, a monoclonal antibody against the B-lymphocyte surface protein CD20, leads to the depletion of B cells. Recently, rituximab was reported to effectively prevent relapses of glucocorticoid-dependent or frequently relapsing minimal change disease (MCD). MCD is thought to be T-cell mediated; how rituximab controls MCD is not understood. In this review, we summarize key cli...
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