Introduction. Computed tomography (CT) has many diagnostic advantages, spurring growth in the number of CT examinations. As the use of CT increases, the potential for radiation-induced adverse effects has become an issue. The primary objective of this study was to assess the liberal use of CT induced radiation exposure in patients with multiple blunt traumas. The secondary objective was to inve...

Cholera toxin (CT) is a mucosal adjuvant capable of inducing strong immune responses to co-administered antigens following oral or intranasal immunization of mice. To date, the direct effect of CT on antigen-specific CD4(+) T cell migration and proliferation profiles in vivo is not well characterized. In this study, the effect of CT on the migration pattern and proliferative responses of adopti...

OBJECTIVE To study the diagnostic yield of specimen obtained by percutaneous renal biopsy (PRB) under CT guidance and Ultrasound (US) guidance. METHODS This study was conducted at the department of Nephrology at Liaquat National Hospital and Dr. Ziauddin Hospital, Karachi. Renal biopsy specimens obtained between January 2007 and September 2009 were studied for number of glomeruli obtained. In...

UNLABELLED The purpose of this study was to investigate the incremental value and diagnostic impact of SPECT/CT in patients who had a solitary spinal lesion on a bone scan. METHODS A prospective study was performed on 80 patients (50 with known cancer) who underwent (99m)Tc-methylene diphosphonate whole-body planar bone scintigraphy and had a solitary spinal lesion. These lesions were then fu...

OBJECTIVE This study sought to develop and evaluate an approach for auditing the semantic completeness of the SNOMED CT contents using a formal concept analysis (FCA)-based model. DESIGN We developed a model for formalizing the normal forms of SNOMED CT expressions using FCA. Anonymous nodes, identified through the analyses, were retrieved from the model for evaluation. Two quasi-Poisson regr...

BACKGROUND The current categorical split of mood disorders in bipolar (BP) disorders and depressive disorders has recently been questioned. The presence of a significant number of manic/hypomanic symptoms in patients with recurrent unipolar depression seems to challenge the traditional dichotomy of unipolar-BP disorder. Two highly unstable personality features, i.e., the cyclothymic temperament...

Objective To evaluate the effect of patient characteristics on popliteal aortic contrast enhancement at lower extremity CT angiography (LE-CTA) scanning. Materials and Methods Prior informed consent to participate was obtained from all 158 patients. All were examined using a routine protocol; the scanning parameters were tube voltage 100 kVp, tube current 100 mA to 770 mA (noise index 12), 0....

PURPOSE To determine the correlation between pretreatment computed tomography (CT) data and survival duration after neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer. MATERIALS AND METHODS 122 consecutive patients with advanced rectal cancer were assessed retrospectively. Pretreatment imaging and postoperative data were evaluated through Kaplan-Meier and Cox proport...

background: to reduce uncertainties of patient positioning, the computerized tomography (ct) images acquired at the treatment planning time can be compared with those images obtained during radiation dose delivery. this can be followed during dose delivery procedure as image guided radiotherapy (igrt) to verify the prescribed radiation dose delivery to the target as well as to monitor radiation...

background: this study set out to evaluate the utility of cerebrovascular virtual non-contrast (vnc) scans. materials and methods: conventional non-contrast (cnc) and dual-energy computed tomography angiography (de-cta) head scans were conducted on 100 subjects, of which 46 were normal, 15 had parenchymal hematomas of the brain, 13 had ischemic infarction, 22 had tumors, and 4 had calcified les...