Herpes simplex virus type 2 (HSV-2) can cause radiculo-myelitis as a neurological manifestation. We report a case of ongoing HSV-2 DNA positivity in the cerebrospinal fluid (CSF) of at least eight weeks under antiviral therapy with acyclovir in a highly immunocompromised hemato-oncologic patient with HSV-2-associated radiculitis. Upon admission, the patient presented with pain, leg paresis, and...

anti n-methyl-d-aspartate receptor (nmdr) encephalitis has been recognized as the most frequent autoimmune encephalitis in children after acute demyelinating encephalomyelitis (adem).however due to the variable the variable clinical presentation, the paucity of specific finding on standard laboratory and radiological investigation remains under recognized. first discribed in 2005, most commonly...

Background: Scrub typhus is a mite-born disease scrub. It commonly manifests as an acute febrile illness with multi-system involvement. regarded life-threatening in children, serious complications usually occurring the 2nd week of illness. Aims and Objectives: The aims this study were to explore clinical laboratory profile children scrub typhus. Materials Methods: All admitted over 1-year durat...

BACKGROUND Meningoencephalitis produce by Koch bacillus is a disease including various symptoms, with often atypical onset and evolution, and with an etiological diagnosis being rarely established. It therefore remains a disease with severe prognosis, despite adequate treatment. CASE REPORT a 47 years old male from Neamt County, with chronic otitis in his recent medical history, comes to the ...

Case Report A 44-year-old right-handed man, with no history of migraine or cardiovascular risk factors, developed acute numbness and weakness involving the right leg and ascending to the right arm and the face, with aphasia and right homonymous hemianopsia. The symptoms cleared within 8 h. Cerebral MR imaging performed 2 h after the onset of symptoms – including T 2 diffusion-weighted fluid-att...

Objective The mechanism of hypoglycorrhachia-low CSF glucose-in meningitis remains unknown. We sought to evaluate the relative contribution of CSF inflammation vs microorganisms (bacteria and fungi) in lowering CSF glucose levels. Methods We retrospectively categorized CSF profiles into microbial and aseptic meningitis and analyzed CSF leukocyte count, glucose, and protein concentrations. We ...

Four patients with Bannwarth's syndrome were examined. One to three weeks weeks after the appearance of a large erythematous skin lesion they developed pain of variable localisation. Four days to four weeks later uni- or bilateral facial palsies and other nerve lesions developed. CSF showed elevated protein and mononuclear pleocytosis. There was a defect of the blood-brain barrier and increased...

Antonios Kerasnoudis, MD Ralf Gold, MD Min-Suk Yoon, MD SECTION 1 A 48-year-old woman was admitted to our department with recurrent episodes of throbbing right parietal headache lasting for hours. The patient was afebrile and neurologic examination disclosed no signs of meningeal irritation or papilledema. Blood pressure (BP) levels and heart rate were normal ( 140/90 mm Hg, 70 bpm) on repeat m...

We report a 67-year-old man with recurrent advanced oropharyngeal squamous cell carcinoma who developed aseptic meningitis, with first symptoms arising approximately 9hours after the first administration of cetuximab, and review the literature to identify key signs and symptoms of this condition. Cetuximab is a monoclonal antibody targeting the epidermal growth factor receptor which has been ra...

background: herpes simplex virus (hsv) is a member of herpesviridae and a leading cause of human viral diseases. meningitis occurs as a complication of hsv-1 or hsv-2 primary infection. objectives: we aimed to evaluate hsv meningitis in children in gorgan province, iran. patients and methods: forty-five cerebrospinal fluid samples were taken from children referred with meningitis symptoms. samp...