A 23-year-old male with a history of bone marrow transplant for acute myeloid leukemia. He presented a large mass in the right inguinal region 5 years ago. Upon physical examination, right-sided cryptorchidism was observed. The tumor markers alpha-fetoprotein and beta-HCG were within normalcy range and lactate dehydrogenase was raised. Computed tomography of the abdomen and pelvis revealed righ...

Introduction: Cryptorchidism has been proved to cause apoptosis in germ cells in respond to changes in the stimulation levels of specific physiological events. The purpose of this study was to determine whether treatment of bilateral cryptorchidism was associated with alterations in testicular gene expression. Methods: To induce bilateral cryptorchid model, immature mice were anesthetized and a...

Chobot (Poland); G Joner (Norway); D Michalkova (Slovakia); C Patterson (Northern Ireland); P Pozzilli (Italy, Lazio); AG Schranz (Malta); P Smail (Scotland); M Songini (Italy, Sardinia); B Urbonaite (Lithuania); E Wadsworth (British Paediatric Survey, UK). Funding: The European diabetes (EURODIAB) research network is supported by the European Commission medical research programme (contracts BM...

The incidence of testicular cancer in cryptorchidism is 30 to 50 times higher than in general population. We present a case of hydronephrosis caused by a seminoma in an abdominal cryptorchid testis. A 22 years old male presented abdominal and right flank pain, and haematuria. Despite the fact that he could not feel right testis since he was 7 years old, he had never looked for treatment. A huge...

Zandbergen and Green (2007) recently described the effect of positional error on the distance between geocoded addresses and major roads, an often-used proxy for traffic-related exposures. They found a 200–500 m range of mean positional errors in their study of 126 Orange County, Florida, public school addresses, a somewhat higher range than that associated with geocodes assigned by four commer...

Despite timely and successful surgery, 32% of patients with bilateral and 10% with unilateral cryptorchidism will develop azoospermia. Cryptorchid boys at risk of azoospermia display a typical testicular histology of impaired mini-puberty at the time of the orchidopexy. During mini-puberty increased gonadotropin and testosterone secretion stimulate transformation of gonocytes into Ad spermatogo...