For the important livestock pathogens classical swine fever virus (CSFV) and bovine viral diarrhea virus (BVDV), cytopathogenic (cp) and non-cp viruses are distinguished according to the induction of apoptosis in infected tissue culture cells. However, it is currently unknown whether cp CSFV differs from non-cp CSFV with regard to virulence in the acutely infected host. In this study, we genera...

Background and objectives: Cisplatin (CP), the chemotherapy drug, is used for the treatment of many types of cancer but causes hepatotoxicity. Zataria multiflora Boiss. (ZM), is a widely used herbal medicine with potent antioxidant properties. This study aimed to assess the protective effect of Zataria multiflora against cisplatin-induced hepatotoxicity. <strong...

An experiment was conducted to determine apparent ileal digestibility of crude protein (CP) and amino acids (AA) and digestible CP and AA of fish meal (FM) in 21-d-old broiler chickens using the regression technique. Four diets containing 0, 1, 2, and 3% FM in place of cornstarch were formulated with FM as the sole contributor of CP and AAs in the sequential diets. Eighty 14-d-old broiler chick...

An evaluation of muscle (pectoralis major) protein turnover using the phenylalanine flood dose technique was assessed in broiler chicks fed graded dietary lysine levels with CP at 170, 210, 250, and 290 g/kg diet. Chicks at 21 d old were injected with 1 mL/100 g BW of a phenylalanine solution (120 micromol L-[ring-2H5)]-phenylalanine). Muscle protein gain was assessed in chicks at 19 and 23 d o...

The short-time self-diffusion D of the globular model protein bovine serum albumin in aqueous (D2O) solutions has been measured comprehensively as a function of the protein and trivalent salt (YCl3) concentration, noted cp and cs, respectively. We observe that D follows a universal master curve D(cs,cp) = D(cs = 0,cp) g(cs/cp), where D(cs = 0,cp) is the diffusion coefficient in the absence of s...

BACKGROUND Several studies have suggested an association between Chlamydophila pneumoniae (Cp) infection and atherosclerosis. A recent study detected Cp DNA in the saphenous vein of 12% of all patients before bypass grafting and in 38% of failed grafts. We used a system in which human veins were perfused with autologous blood under arterial pressure. MATERIALS AND METHODS Veins were surplus s...

Peroxisome proliferator-activated receptor-α (PPARα) activation attenuates cisplatin (CP)-mediated acute kidney injury by increasing fatty acid oxidation, but mechanisms leading to reduced renal triglyceride (TG) accumulation could also contribute. Here, we investigated the effects of PPARα and CP on expression and enzyme activity of kidney lipoprotein lipase (LPL) as well as on expression of a...

Cerato-platanin (CP) is a secretion protein produced by the fungal pathogen Ceratocystis platani, the causal agent of the plane canker disease and the first member of the CP family. CP is considered a pathogen-associated molecular pattern because it induces various defense responses in the host, including production of phytoalexins and cell death. Although much is known about the properties of ...

We determined the optimum dietary protein level in juvenile barred knifejaw Oplegnathus fasciatus in cages. Five semi-purified isocaloric diets were formulated with white fish meal and casein-based diets to contain 35, 40, 45, 50, and 60 % crude protein (CP). Fish with an initial body weight of 7.1 ± 0.06 g (mean ± SD) were randomly distributed into 15 net cages (each size: 60 cm × 40 cm × 90 c...