OBJECTIVES/HYPOTHESIS To determine the relative risk of having eosinophilic esophagitis (EoE) coexist with chronic rhinosinusitis (CRS) in probands and their families using the Utah Population Database (UPDB). METHODS This retrospective observational cohort study with population-based matched controls utilized the UPDB, a genealogical database linked to medical records. It was used to identif...

OBJECTIVE To evaluate the effectiveness of crenotherapy on the olfactory performance of elderly patients with chronic rhinosinusitis (CRS). STUDY DESIGN A longitudinal case-control study of a cohort of elderly patients affected by CRS and olfactory dysfunction assessed with the Sniffin' Sticks (Burghart Medical Technology, Wedel, Germany) (SS) olfactory test. METHODS One hundred and thirty-...

BACKGROUND Type 4 cardiorenal syndrome (CRS) refers to the cardiac injury induced by chronic kidney disease. We aimed to assess oxidative stress and cardiac injury in patients with type 4 CRS, determine whether the antioxidant apocynin attenuated cardiac injury in rats with type 4 CRS, and explore potential mechanisms. METHODS AND RESULTS A cross-sectional study was conducted among patients w...

Acute cardiorenal syndrome (CRS) corresponds to an association of acute heart failure and a worsening of renal function. The detection of acute kidney injury (AKI) unfortunately occurs at a late stage of CRS, leading to an increased mortality of the patients. In this review, we described the pathophysiology of CRS and discussed the potential interest of biochemical biomarkers (namely creatinine...

The achievable rate of an opportunistic nonorthogonal multiple access (O-NOMA) based cooperative relaying system (CRS) with channel state information (CSI) available at the transmitter end is analyzed under Rician fading channels. O-NOMA-based CRS achieves better achievable rate than CNOMA-based CRS and results are verified through Monte Carlo simulations. Keywords—Non-orthogonal Multiple Acces...

EMRs are essential in modern healthcare. At the same time there has been the rapid development of clinical research systems (CRS) which offer specific tools to facilitate research protocol development, execution and management. However, examples of integrating a commercial EMR and CRS are rare. We describe our experience in the analysis, resolution of issues, design, and implementation of EMR/C...

CRS based on radiographic criteria. Based on these data and analysis, we can use the CT scan to discriminate between children with and without CRS. Nevertheless, the positive and negative predictive values of this test are substantially dependent on the prevalence of CRS, and this must be factored into clinical decision-making. This study highlights the fact that CRS is primarily a clinical dia...

INTRODUCTION Chronic rhinosinusitis (CRS) is a multifactorial disease. Allergies are considered a predisposing factor to CRS; however, this remains controversial. The objective of this research was to investigate the prevalence of co-morbidities and allergic reaction, and to specify the most common allergens in patients with confirmed CRS. MATERIALS AND METHODS One hundred patients with signs...

OBJECTIVE Previous investigation demonstrated predominantly lymphocytic inflammation in sinus mucosa of young children with chronic rhinosinusitis (CRS) rather than eosinophilic inflammation typical of adult CRS. Immunohistopathological study was undertaken to define further the cellular response in pediatric CRS. STUDY DESIGN Maxillary mucosal biopsies from children and adults with CRS were ...

Background. As part of regional elimination efforts, rubella-containing vaccines (RCV) have recently been introduced in the Philippines, yet the true burden of rubella and congenital rubella syndrome (CRS) in the country is largely unknown. Objective. To provide baseline information on rubella and CRS prior to routine vaccine introduction in the Philippines. Methods. We conducted a systematic l...