A mathematical analysis has been carried out for the axial flow of a Bingham plastic fluid, in the Concentric Cylinder Viscometer which consists of a cylindrical sample holder (the cup) and a cylindrical spindle (the bob) coaxial with the cup. The fluid to be tested flows through the annular gap of the cup and the bob system, sheared by the rotation of the inner cylinder, while the outer cy...

Reduced shear stress and augmented oscillatory shear rate are associated with the proatherogenic phenotype observed with aging. To date, mechanisms contributing to the age-related alterations in shear rate in humans have only been examined in the conduit vessels of the arm. Therefore, this study sought to examine the contribution of nitric oxide (NO) bioavailability to age-related alterations i...

As dust settles in a protoplanetary disk, a vertical shear develops because the dust-rich gas in the midplane orbits at a rate closer to true Keplerian than the slower-moving dust-depleted gas above and below. A classical analysis (neglecting the Coriolis force and differential rotation) predicts that Kelvin-Helmholtz instability occurs when the Richardson number of the stratified shear flow is...

Adenosine triphosphate (ATP) is a regulatory molecule for many cell functions, both for intracellular and, perhaps less well known, extracellular functions. An important example of the latter involves red blood cells (RBCs), which help regulate blood pressure by releasing ATP as a vasodilatory signaling molecule in response to the increased shear stress inside arterial constrictions. Although s...

The suppression of the regenerative chatter phenomenon in turning process via the variation of the frequency and amplitude of the spindle motor excitation is carried out in this research. A programmable inverter is employed for variable periodic excitation of the spindle motor. A set of turning experiments is designed and performed on a number of conical work pieces both in constant spindle spe...

BACKGROUND The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor binding under shear conditions remains unclear. We sought to determine where activated factor X (F...

Fibrin (Fn) deposition defines several type 1 immune responses, including delayed-type hypersensitivity and autoimmunity in which polymorphonuclear leukocytes (PMNs) are involved. Fn monomer and fibrinogen are multivalent ligands for a variety of cell receptors during cell adhesion. These cell receptors provide critical linkage among thrombosis, inflammation, and cancer metastasis under venous ...

Three types of shear stud arrangement, respectively featuring an orthogonal, a radial and a critical perimeter pattern, were evaluated numerically. A numerical investigation was conducted using the finite element software ABAQUS to evaluate their ability to resist punching shear in a flat plate. The finite element analysis here is an application of the nonlinear analysis of reinforced concrete ...

This paper studies the reliability of infinite slopes in the presence of spatially variable shear strength parameters that increase linearly with depth. The mean trend of the shear strength parameters increasing with depth is highlighted. The spatial variability in the undrained shear strength and the friction angle is modeled using random field theory. Infinite slope examples are presented to ...