Background Proliferative lupus nephritis (LN) is characterized histologically by glomerular and tubulointerstitial (TI) inflammation that presumably must resolve with treatment to achieve remission. Here we sought document the trajectory of lesion resolution using serial kidney biopsies during LN treatment. Methods A cohort proliferative patients was prospectively followed sta...

The yellow crescent or myoplasm is a localized cytoplasmic region in eggs of the ascidian Styela that is partitioned to the larval tail muscle and mesenchyme cells during embryonic development. To determine whether the myoplasm contains a specific subset of maternal macromolecules, its abundant proteins and mRNAs were identified and compared to those present in the remainder of the egg. This wa...

Fibrillary glomerulonephritis is an unusual, but not rare cause of glomerulonephritis. Hypocomplementemia in association with fibrillary glomerulonephritis has been reported only once previously. A patient with hypocomplementemia and fibrillary deposits as demonstrated by electronmicroscopy is reported. The clinical and pathologic features of fibrillary glomerulonephritis and immunotactoid glom...

bone marrow showed active marrow and normal granulocyte precursors, and he was started on methotrexate. He demonstrated a good initial response to methotrexate 7.5 mg weekly, but this was stopped due to neutropenia of 0.9 Â 10 9 /l. Cyclosporin was unsuccessful (gum hypertrophy and hypertension). Methotrexate was restarted, but with persisting asymptomatic neutropenia varying between 0.57 and 0...

AIM To achieve retention in severely resorbed mandibular ridges during impression making and to maintain the retention and stability of these dentures during function. BACKGROUND No good method with adequate clinical photographs that will empower the dentist with the necessary skill has been reported in the literature. TECHNIQUE The technique involves making a preliminary impression in algi...