Business processes are becoming more and more complex and at the same time their correctness is becoming a critical issue: The costs of errors in business information systems are growing due to the growing scale of their application and the growing degree of automation. In this paper we consider Extended Event-driven Process Chains (eEPCs), a language which is widely used for modeling business ...

Abstract Background Common peroneal nerve (CPN) injury is one of the most common injuries in lower extremities and motor functional recovery injured was often unsatisfactory, mechanism which still controversial. The purpose this retrospective study to determine prognostic factors patients who underwent surgery for CPN provide a tool clinicians assess patients’ prognosis. Methods This cohort all...

OBJECTIVE The objective of this study is to compare the efficacy of central (single) vs bilateral (2-injections) endoscopic ultrasound (EUS)-celiac plexus neurolysis (CPN) for palliation of patients with pain related to pancreatic cancer. MATERIALS AND METHODS Patients with unresectable pancreatic cancer were included. Central EUS CPN was used in the first group and bilateral EUS CPN in the s...

The obligate intracellular, gram-negative bacterium Chlamydophila pneumoniae (Cpn) has impact as a human pathogen. Little is known about changes in the Cpn transcriptome during its biphasic developmental cycle (the acute infection) and persistence. The latter stage has been linked to chronic diseases. To analyze Cpn CWL029 gene expression, we designed a pathogen-specific oligo microarray and op...

Nitration of protein tyrosine residues by nitric oxide (NO)-derived reactive species results in the production of stable nitrotyrosine (NT) moieties that are immunochemically detectable in many regions of normal brain and enriched in those areas containing constitutive nitric oxide synthase (cNOS). These include the caudate-putamen nucleus (CPN) and the globus pallidus, which receives major inh...

The paper presents some of the results obtained by studying Petri nets’ capability for modeling and analysis of Supply Chain performances. It is well known that the absence of coordination in Supply Chain management causes the so-called Bullwhip Effect, in which fluctuations in orders increase as they move up the chain. A simple three-stage supply chain with one player at each stage – a retaile...

The mammalian neocortex is parcellated into anatomically and functionally distinct areas. The establishment of area-specific neuronal diversity and circuit connectivity enables distinct neocortical regions to control diverse and specialized functional outputs, yet underlying molecular controls remain largely unknown. Here, we identify a central role for the transcriptional regulator Lim-only 4 ...

Repair of specific neuronal circuitry in the neocortex may be possible via neural precursor transplantation or manipulation of endogenous precursors in situ. These approaches will almost certainly require a detailed understanding of the mechanisms that control survival and differentiation of specific neuronal lineages. Such analysis has been hampered by the overwhelming diversity of neuronal ty...

Abstract Background Isolated common peroneal neuropathy (CPN) is the most lower extremity mononeuropathy and third overall in adults. It often associated with multiple aetiologies, such as trauma, hereditary neuropathies iatrogenic causes. We report a rare case of acute bilateral foot drop late adolescent female following rapid weight loss attributable to intermittent fasting diet. Case present...

We present an interdisciplinary approach that, by incorporating a range of experimental and computational techniques, allows the identification and characterization of functional/immunogenic domains. This approach has been applied to ArtJ, an arginine-binding protein whose orthologs in Chlamydiae trachomatis (CT ArtJ) and pneumoniae (CPn ArtJ) are shown to have different immunogenic properties ...