The antiandrogenic and gestagenic steroid cyproterone acetate (CPA) has been widely used in human therapy. There is currently a debate about the safety of CPA, since it proved to be genotoxic in rat liver and human hepatocytes [I. Neumann et al., Carcinogenesis (Lond.), 13: 373-378, 1992, J. Topinka et al., Carcinogenesis (Lond.), 14: 423-427, 1993, L. R. Schwarz et al., Biological Reactive Int...

Continuous four hours EEG (electroencephalogram) recordings and its power spectrum analysis using fast fourier transform (FFT) in urethane anesthetized male Charles Foster rats were performed in two groups: open brain injury and p-CPA (para-Chlorophenylalanine) pretreated before brain injury, respectively, and compared with the EEG power spectrum of control rats. The EEG power spectrum analysis...

We find mathematically optimal side-channel distinguishers by looking at the side-channel as a communication channel. Our methodology can be adapted to any given scenario (device, signal-to-noise ratio, noise distribution, leakage model, etc.). When the model is known and the noise is Gaussian, the optimal distinguisher outperforms CPA and covariance. However, we show that CPA is optimal when t...

Power analysis attacks are based on analyzing the power consumption of the cryptographic devices while they perform the encryption operation. Correlation Power Analysis (CPA) attacks exploit the linear relation between the known power consumption and the predicted power consumption of cryptographic devices to recover keys. It has been one of the effective side channel attacks that threaten the ...

Cyclopiazonic acid (CPA) is a sarcoplasmic reticulum Ca2+-ATPase inhibitor that increases intracellular calcium. The role of CPA in regulating the oxidation and esterification of palmitate, the hydrolysis of intramuscular lipids, and the activation of hormone-sensitive lipase (HSL) was examined in isolated rat soleus muscles at rest. CPA (40 micro M) was added to the incubation medium to levels...

The cytosolic aldehyde dehydrogenase (ALDH) isozyme from cyclophosphamide (f PA) resistant 1.1210 cells (L1210/CPA) was purified to apparent homogeneity using ternary enzyme complex-dye ligand chromatography. The purified isozyme migrates as a single band at M, 51,000 in sodium dodecyl sulfate polyacrylamide gel electrophoresis and as a single charge species at isoelectric point = 5.8 in isoele...

Crystallization by particle attachment (CPA) is a gradual process where each step has its own thermodynamic and kinetic constrains defining unique pathway of crystal growth. An important example biomineralization calcium carbonate through amorphous precursors that are morphed into shapes textural patterns cannot be envisioned the classical monomer-by-monomer approach. Here, mechanistic link bet...

We analyze intermittency in intensity and fluorescence lifetime of CsPbBr3 perovskite quantum dots by applying unbiased Bayesian inference analysis methods. apply change-point (CPA) a state clustering algorithm to determine the timing switching events number states between which occurs statistically manner, we have benchmarked particularly highly multistate emitters. conclude that display pleth...

BACKGROUND & OBJECTIVE Clostridium perfringens type A (CPA) isolates produce lethal necrotizing antigens and the heat resistant forms of the organism are associated with pathogenic outcome in humans. CPA has also been implicated in antibiotic associated diarrhoea (AAD). We therefore undertook this study to investigate the presence of CPA in stool samples of patients with AAD in a tertiary care ...