نتایج جستجو برای: cox 2 inhibitory

تعداد نتایج: 2641865  

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2006

Journal: :Osteoarthritis and Cartilage 1999

2015
Sandra Gouveia-Figueira Jessica Karlsson Alessandro Deplano Sanaz Hashemian Mona Svensson Marcus Fredriksson Sundbom Cenzo Congiu Valentina Onnis Christopher J. Fowler Alessio Lodola

BACKGROUND Increased endocannabinoid tonus by dual-action fatty acid amide hydrolase (FAAH) and substrate selective cyclooxygenase (COX-2) inhibitors is a promising approach for pain-relief. One such compound with this profile is 2-(2-fluorobiphenyl-4-yl)-N-(3-methylpyridin-2-yl)propanamide (Flu-AM1). These activities are shown by Flu-AM1 racemate, but it is not known whether its two single ena...

Journal: :Japanese Journal of Clinical Immunology 2000

2011
Afshin Zarghi Sara Arfaei

Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (PGs). Their use is associated with the side effects such as gastrointestinal and renal toxicity. The therapeutic anti-inflammatory action of NSAIDs is produced by the inhibition of COX-2, while the ...

Journal: :Food chemistry 2013
Souhila Boudjou B Dave Oomah Farid Zaidi Farah Hosseinian

Two faba bean (Vicia faba L.) subspecies major and minor and lentil seeds grown in Algeria were separated into cotyledons and hulls. These fractions, together with their corresponding whole seeds, were extracted with two solvents, aqueous (70%) acetone and (80%) ethanol, and evaluated for antioxidant activity in relation to their phenolic contents. Acetone selectively extracted tannins from fab...

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