Non-alcoholic fatty liver disease (NAFLD) often manifests as the liver component of obesity, diabetes and the metabolic syndrome, and ranges from fat accumulation to steatohepatitis, and sometimes to fibrosis/cirrhosis. The high prevalence (5–20 % in the general population) of this disorder accounts for an increased incidence of end-stage liver disease and hepatocellular carcinoma in many parts...

This study aims to the impact of environmental stresses on chemical compositions essential oils and content secondary metabolites plants most used by rural population: Thymus vulgaris, Mentha pulégium Rosmarinus officinalis. The results indicate that percentage increased in second year when temperature water pressure 50%. Specifically, coumarin from 3.94% 9.23%, saponins 6.17% 7.78%, tannins 2....

Background: Wound healing is one of the main problems faced by medical scientists. Nowadays, herbal compounds are used to accelerate the repairing process. Coumarin is a plant compound with anti-inflammatory and anti-oxidant effects. In the present study, the benefits of using coumarin in accelerating wound healing were investigated in mice.Methods: Sixty...

Coumarin-PVA is deposited onto p-Si wafers using the spin coating technique. I examined fundamental electrical variables of Al/CoumarinPVA/p-Si type Schottky barrier diodes (SBDs), by utilizing capacitance/voltage(C-V) and conductance/voltage (G-V) measurements at different frequencies varied from 10kHz to1MHz. have thoroughly explored how CoumarinPVA interlayer, series resistance (Rs) surfac...

INTRODUCTION Cinnamon is currently marketed as a remedy for obesity, glucose intolerance, diabetes mellitus and dyslipidaemia. Integrative medicine is a new concept that combines conventional treatment with evidence-based complementary therapies. AIM The aim of this review is to critically evaluate the experimental evidence available for cinnamon in improving glycaemic targets in animal model...

Active development of compact analytical instruments suitable for point-of-care testing (POCT) requires optimization of existing methods. To aid the development of capillary gel electrophoresis instruments for POCT, we attempted to separate polymerase chain reaction products (small DNAs) using a short, fused silica capillary coated with an acrylamide (AM)/acrylic acid (AA) copolymer (poly(AM-co...

Subcritical water extraction of horse chestnut (Aesculus hippocastanum) parts, such as seeds, seed shell, bark and leaves has been performed in a batch reactor at temperatures 150, 200 250?C times 5, 15 30 min. The obtained extracts were analyzed by spectrophotometric methods to determine the total phenols, carbohydrates antioxidant activity. Furthermore, compounds detected extracts, triterpene...

The title compound, C21H14N2O2, was prepared by Pictet-Spengler cyclization of tryptamine and 4-formyl coumarin. In the mol-ecule, the dihedral angle between the mean planes of the coumarin and β-carboline ring systems is 63.8 (2)°. In the crystal, mol-ecules are linked via N-H⋯N hydrogen bonds, forming chains along the b-axis direction. Within the chains, there are a number of offset π-π inter...

In the title compound, C(26)H(26)N(2)O(2)S, the dihedral angle between the benzothia-zole and coumarin rings is 8.34 (7)°, indicating that the overall benzothia-zole substituent is almost coplanar with the coumarin rings. An intra-molecular S⋯O [2.813 (1) Å] contact may help to stabilize the mol-ecular conformation. In the crystal structure, π-π stacking inter-actions [centroid-centroid distanc...

In the title compound, 6-benz-yloxy-2H-1-benzopyran-2-one, C(16)H(12)O(3), the coumarin unit and benzyl plane in the mol-ecule are perpendicular to each other [86.92 (7)°]. The crystal packing is stabilized by π-π stacking inter-actions, with an inter-planar separation between inversion-related coumarin units of 3.618 (3) Å. The crystal structure shows inter-molecular C-H⋯O hydrogen bonding bet...