Electroencephalography (EEG)-based measurements of fine tactile sensation produce large amounts data, with high costs for manual evaluation. In this study, an EEG-based machine-learning (ML) model support vector machine (SVM) was established to automatically evaluate post-stroke impairments in sensation. Stroke survivors (n = 12, stroke group) and unimpaired participants 15, control received st...

Anger is associated with various responses. Research on the neuroscience of anger has revealed that greater left than right frontal cortical activity is associated with angry approach-oriented responses, such as aggression, whereas greater right than left frontal cortical activity is associated with inhibited angry responses mixed with anxiety. In the current research, we extended these past st...

Transcranial magnetic stimulation (TMS) is a safe, noninvasive, and painless way to stimulate the human motor cortex in behaving human subjects. When it is applied as a single-pulse, measurements such as central conduction time, motor threshold, silent-period duration, recruitment curve, and mapping of muscle representation can be determined. Paired-pulse TMS is a useful way to examine cortical...

Many studies have investigated the evidence for tactile and visual interactive responses to activation of various brain regions. However, few studies have reported on the effects of visuo-tactile multisensory integration on the amount of brain activation on the somatosensory cortical regions. The aim of this study was to examine whether coincidental information obtained by tactile stimulation c...

When we fall asleep, consciousness fades yet the brain remains active. Why is this so? To investigate whether changes in cortical information transmission play a role, we used transcranial magnetic stimulation together with high-density electroencephalography and asked how the activation of one cortical area (the premotor area) is transmitted to the rest of the brain. During quiet wakefulness, ...

1. Cyclic adenosine 3’,5’-monophosphate and N6-2’-Odibutyryl cyclic adenosine 3’,5’-monophosphate stimulate the active cellular entry and cumulative uptake of several amino acids in rat kidney cortex slices. 2. Parathyroid hormone, known to augment cellular production of cyclic adenosine 3’,5’-monophosphate by stimulating renal cortical adenyl cyclase, increases the renal cortical uptake of ami...

Transcranial direct current stimulation (tDCS) is a non-invasive stimulation technique that can be applied to modulate cortical activity through induction of cortical plasticity. Since various neuropsychiatric disorders are characterized by fluctuations in cortical activity levels (e.g., schizophrenia), tDCS is increasingly investigated as a treatment tool. Several studies have shown that the i...

In the present study, we investigated neuronal responses to acoustic stimuli and cortical stimulation in the medial geniculate body (MGB) through in vivo intracellular recordings in anaesthetized guinea pigs. Of the 54 neurones examined with acoustic stimuli, 36 showed excitatory postsynaptic potential (EPSP) responses and 19 showed inhibitory postsynaptic potential (IPSP) responses to acoustic...

Attention-deficit hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in the pediatric population. The clinical management of ADHD is currently limited by a lack of reliable diagnostic biomarkers and inadequate therapy for a minority of patients who do not respond to standard pharmacotherapy. There is optimism that noninvasive brain stimulation may help to ad...