نتایج جستجو برای: cortical dysplasia

تعداد نتایج: 133004  

Journal: :Bangladesh journal of neurosurgery 2023

Focal cortical dysplasias (FCDs) belong to the large spectrum of malformations development (MCDs) and represent most common structural brain lesion in children with drug-resistant focal epilepsies submitted surgical treatment. It is responsible for nearly half intractable epilepsy cases adults, at same time it characterized by quite good treatment outcome. We describe a case where young girl ha...

2015
Achira Roy Jonathan Skibo Franck Kalume Jing Ni Sherri Rankin Yiling Lu William B Dobyns Gordon B Mills Jean J Zhao Suzanne J Baker Kathleen J Millen Sean J Morrison

Mutations in the catalytic subunit of phosphoinositide 3-kinase (PIK3CA) and other PI3K-AKT pathway components have been associated with cancer and a wide spectrum of brain and body overgrowth. In the brain, the phenotypic spectrum of PIK3CA-related segmental overgrowth includes bilateral dysplastic megalencephaly, hemimegalencephaly and focal cortical dysplasia, the most common cause of intrac...

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