The synthesis of progesterone by the corpus luteum is essential for the establishment and maintenance of early pregnancy. Regulation of luteal steroidogenesis can be broken down into three major events; luteinization (i.e., conversion of an ovulatory follicle), luteal regression, and pregnancy induced luteal maintenance/rescue. While the factors that control these events and dictate the final s...

heterotopic pregnancy is rare under natural circumstance (conception). we report the first case of heterotopic pregnancy in spontaneous conception with four previous caesarean sections and ruptured tubal ectopic with resultant successful normal intra-uterine pregnancy delivered at term after salpingectomy. a 32-year-old gravida 5 para 4+0 with 3 living children, with 4 previous caesarean sectio...

ovarian follicle response and corpus luteum formation following induction of ovulation using gonadotropin-releasing hormone (gnrh) analogues and luteinizing hormone (lh) in bactrian camel were characterized. bactrian camels with a mature follicle (13-19.6 mm) received: 1) natural porcine lh (25 mg, iv, n = 4), 2) buserelin (20 μg, iv, n = 4) and 3) alarelin (25 μg, im, n = 4). daily ultrasonogr...

In the mammalian ovary, follicular and corpus luteum cycle is associated with intensive microvascular remodelling. The complex angiogenic dynamics are finely tuned by numerous regulatory factors acting as activators (up-regulators) or inhibitors (down-regulators) of angiogenesis. Alterations of such a tight modulation are involved in several pathologies, including infertility, polycystic ovaria...

The presence of adenosine 3’,5’-monophosphate was demonstrated in bovine luteal tissue. The addition of luteinizing hormone to incubating slices of a bovine corpus luteum caused a rapid accumulation of this cyclic nucleotide which preceded the increase in progesterone synthesis. This effect appeared to be specific for luteinizing hormone. Puromycin did not inhibit this action of luteinizing hor...

BACKGROUND The aim of this study was to investigate the presence of MMP-14 and MMP-2 during human ovarian follicular development using immunohistochemistry, and the activity of MMP-2 in follicular fluid using zymography. METHODS Ovarian tissue collected from the archives of the Department of Pathology was examined and medical records and histopathology were reviewed. Follicular fluids were co...

Rhinopoma microphyllum kinneari is an insectivorous microchiropteran, breeding once in a year. Histochemical localisation of two dehydrogenases viz., succinate dehydrogenase (SDH) and lactate de hyd ro ge na se (LDH), was achieved in the ovaries of bats obtained during non-pregnant, pregnant and lacta ting stages. Differential enzyme activities in different structures of the ovaries were visual...

A 25year old P2+1 woman presented to the gynaecology emergency unit at the Federal Medical Centre Gombe with a one day history of abdominal pain and dizziness. Ultrasound scan diagnosis was that of acute ruptured ectopic pregnancy. She had emergency exploratory laparotomy with right oophorectomy. Histology revealed ruptured corpus luteum cyst. The management pitfalls are highlighted.