Patients with syndrome X, defined as angina without demonstrable obstructive epicardial coronary artery disease, have been the subject of multiple investigations evaluating the pathophysiology of this syndrome. Multiple aetiologies have been proposed to explain the mechanism of ischaemia including endothelial dysfunction, microvascular hyperresponsiveness, and hyperadrenergic state. Interesting...

We present a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma, or the Samter-Beer triad of asthma, nasal polyps, and aspirin allergy. The Kounis-Zavras syndrome, also known as Kounis syndrome, leads to angina pectoris or acute coronary syndrome secondary to coronary vasospasm in response to an allergic stimulus, leading to mast-cell degranulation of vasospastic mediators....

A rare clinical case of malformation the coronary arteries is considered – anomalous left artery from pulmonary (Bland-WhiteGarland syndrome) in a 61-year-old patient. Detailed visualization form angiograms and multispiral-CT, including those after surgery, presented.

AIMS Diabetic patients with coronary artery disease (CAD) are often free of chest pain syndrome. A useful modality for non-invasive assessment of CAD is coronary computed tomography angiography (CTA). However, the prognostic value of CAD on coronary CTA in diabetic patients without chest pain syndrome is relatively unknown. Therefore, the aim was to investigate the long-term prognostic value of...

INTRODUCTION Inflammation has been implicated in the development of atherosclerosis in patients with acute coronary syndrome. C-reactive protein is an established nonspecific prognostic inflammatory biomarker for patients with acute coronary syndrome in the medical literature. This has led to a concerted effort to identify circulating inflammatory biomarkers to facilitate predicting the risk fo...

STUDY OBJECTIVE Coronary computed tomographic (CT) angiography has excellent performance characteristics relative to coronary angiography and exercise or pharmacologic stress testing. We hypothesize that coronary CT angiography can identify a cohort of emergency department (ED) patients with a potential acute coronary syndrome who can be safely discharged with a less than 1% risk of 30-day card...

BACKGROUND Holt-Oram syndrome (HOS) is a rare but significant syndrome consisting of structural heart defects, conduction abnormalities, and upper extremity anomalies. It was first described in the British Heart Journal in 1960 by Mary Holt and Samuel Oram as a report of atrial septal defect, conduction disturbances, and hand malformations occurring in family members. Patients can present with ...

Dear editor Regarding the duration of supplement therapy in our study which has been published in the Avicenna J Phytomed, 2019; 9(1): 1-9, “The effects of curcumin on the prevention of atrial and ventricular arrhythmias and heart failure in patients with unstable angina” (Dastani et al., 2019),  some critical flaws has been mentioned. Primarily, we are grateful for the consi...

A positive family history is a recognized cardiovascular risk factor, and genome-wide scans may reveal susceptibility loci for coronary artery disease. The acute coronary syndrome, consisting of myocardial infarction and unstable angina, is the most important manifestation of coronary disease and is characterized by atherosclerotic plaque disruption and coronary thrombosis. From approximately 6...