Recent data from in vitro, animal, and human studies have shed new light on the positive roles of copper in many aspects of AD. Copper promotes the non-amyloidogenic processing of APP and thereby lowers the Aβ production in cell culture systems, and it increases lifetime and decreases soluble amyloid production in APP transgenic mice. In a clinical trial with Alzheimer patients, the decline of ...

Melanin is a pigment produced by laccase, a phenoloxydase enzyme, and is related to the virulence of Cryptococcus neoformans as it is also considered an adaption mechanism to environmental conditions and protection against UV radiation, phagocytic system attack and antifungal drugs. Laccase synthesis is stimulated by several factors, including copper metabolism. The current study shows C. neofo...

Synonyms, trade names and molecular formulae for cadmium, cadmium-copper alloy and some cadmium compounds are presented in Thble 1. The cadmium compounds shown are those for which data on carcinogenicity or mutagenicity were available or which are commercially important compounds. It is not an exhaustive list and does not necessarily include all of the most commercially important cadmium-contai...

The literature dealing with the electrochemical corrosion of copper and possibility of its prevention using inhibitors is examined. Inorganic compounds are investigated as well, but organic compounds and their derivatives in much greater numbers. Researches are directed to influence of compounds structure, concentration, method of application as well as media that inhibitor is used in on inhibi...

New oxidative dehydrogenative couplings of pyrazol-5-amines for the selective synthesis of azopyrrole derivatives have been described. The former reaction simultaneously installs C-I and N-N bonds through iodination and oxidation, whereas the latter involved a copper-catalyzed oxidative coupling process. The resulting iodo-substituted azopyrroles were employed by treatment with various terminal...

CuBr(2) with 2,2,6,6-tetramethylpiperidyl-1-oxy (TEMPO) has been successfully employed for the aerobic oxidation of primary and secondary benzyl amines in aqueous acetonitrile. Such catalytic systems have previously been used extensively in alcohol oxidation reactions. The same catalyst system was also used for oxidative cross-couplings of benzylamines with anilines. The electronic and steric p...

A simple synthetic strategy has been developed for accessing internally functionalized dendrimers. The key feature of this approach is the use of two orthogonal and efficient reactions--'epoxy-amine' and 'thiol-ene' coupling--for rapid growth of the dendritic scaffold. This sequence of reactions allows for the introduction of reactive hydroxyl groups at each dendritic layer.

Aim: This study is aimed at designing a bioremediation model using microbes against Cu pollution. Methods And Results: For this purpose, copper resistant bacteria were isolated from industrial areas and were characterized for its copper accumulating properties using various methods including copper accumulation, optimization, Antibiotic resistance, production of thiols, plasmid curing, SEM. The...

Copper is common element in the environment. People are exposed to copper by breathing air, drinking water, eating food, and by skin contact with soil, water and other copper-containing substances. Most copper compounds found in air, water, sediment, soil and rock are strongly attached to dust and dirt or imbedded in minerals. It rapidly enters into the bloodstream and is distributed throughout...