ABSTRACT Sterculia gum is a complex polysaccharide of high molecular weight. The rapid swelling of gum particles, their relative insolubility and their unusual resistance to bacterial and enzymatic breakdown make this gum suitable as a bulk laxative. The present work deals with development of granular formulation using Sterculia gum and its evaluation. The evaluation includes size gradation usi...

To assess mutans streptococci (MS) during xylitol gum chewing (mean 3.8 g/day, 2.9 times/day) for 13 months and then for 15 months after the intervention, Japanese mothers with high salivary MS were randomized into two groups: xylitol gum (n = 56) and no gum (n = 51). The proportion of low MS levels was highest at 3 months of consumption (48.8%), but was significantly lower compared to baseline...

Polysaccharide-polysaccharide interactions are attractive in the food, polymer and pharmaceutical systems because they may impart novel or improved functional properties to products and reduce costs. In this work, the rheological interaction of sage seed gum (SSG) as a novel hydrocolloid with xanthan gum (XG) was studied in the dilute region. The intrinsic viscosity of the XG-SSG mixture at fiv...

BACKGROUND In 1996, the US Food and Drug Administration (FDA) approved switching nicotine gum and patch from prescription to over-the-counter (OTC) status. Some expressed concerns that broader availability and lack of physician control might increase persistent use of nicotine replacement therapy (NRT)-that is, use beyond the period specified by the FDA approved label. OBJECTIVE To estimate t...

This was a single-center, prospective, cross-sectional study stratified by age and gender with the objective of determining the relationship between gum chewing history, salivary flow, and dental caries severity in adults. We enrolled 191 subjects aged 18-65 years who underwent assessments for gum chewing history, unstimulated salivary flow rate, salivary pH, and caries severity. Unstimulated s...

OBJECTIVES The present study examined the effect of chewing gum on sustained attention and associated changes in subjective alertness. METHODS In a within-participants design, 20 participants completed an extended version of the sustained attention response task (SART: Robertson et al., 1997), both with and without chewing gum. Self-rated measures of alertness, contentedness, and calmness wer...

Binders are agents employed to impart cohesiveness to the granules. This ensures the tablet remains intact after compression. The development of new excipients for potential use as binding agent in tablet formulations continues to be of interest. This is because different binding agents can be useful in achieving various tablet mechanical strength and drug release properties for different pharm...

We examine the impact of chewing gum on a Bakan-type vigilance task that requires the continual updating of short-term order memory. Forty participants completed a 30-min auditory Bakan-task either with, or without, the requirement to chew gum. Self-rated measures of mood were taken both pre- and post-task. As expected, the vigilance task produced a time-dependent performance decrement indexed ...

Steady shear flow properties of Acacia tortuosa gum aqueous dispersions at different concentrations (15–40% w/v) were studied at 20 C using a controlled shear rate Couette rheometer and Mooney–Ewart sensor systems. Flow curves showed shear thinning non-Newtonian behaviour with a tendency to a Newtonian plateau at high-shear rate. The results obtained fitted the Sisko model very well. The influe...

OBJECTIVE The aim of this study was to examine, after setting several restorations, the influence of adjusted occlusal interference during gum chewing on blood flow in the prefrontal area as determined using near-infrared spectroscopy. MATERIAL AND METHODS The physiological rate was assessed using a visual analog scale (VAS) questionnaire. We selected 16 patients who desired prosthetic restor...