Metastatic disease is linked to TERT promoter mutations in conjunctival melanomas (CM). Both and ATRX are associated with faulty telomere maintenance. This study aimed determine the prognostic value of loss melanocytic lesions. Eighty-six lesions from Rotterdam Ocular Melanoma Study group were collected. status determined using immunohistochemical staining molecular diagnostics, respectively. N...

purpose: to evaluate and compare the results of different surgical methods for post-trabeculectomy bleb revision at labbafinejad medical center, tehran-iran, from 1999 to 2003. methods: this study was conducted on all patients who underwent post-trabeculectomy bleb revision due to hypotony [intraocular pressure (iop) less than 6 mmhg] or bleb leakage. surgical methods were: conjunctival advance...

AIMS/BACKGROUND Ten patients with metastatic tumours to the conjunctiva and the clinical aspects of this rare form of ocular metastasis are described in this study. METHOD All patients with ocular and adnexal metastatic tumours referred to an ocular oncology service were reviewed and those having conjunctival metastases were studied for the site of their primary tumour, clinical features, and...

Background/Aim: This study analysed the prevalence of characteristics evaluated in dermatoscopy for melanocytic infiltrations conjunctiva with various degrees malignancy. Patients and Methods: A total 160 conjunctival pigmented lesions were studied. Each lesion was scored using dermatoscopic patterns malignancy described by Kittler. Also, Authors’ own clues added to evaluation. Results: In mela...

Although many clinicopathological studies of malignant melanoma of the conjunctiva have been reported, there have been no studies of the expression and gene mutations of KIT and PDGFRA in melanoma of the conjunctiva. A 69-year-old Japanese woman consulted our hospital because of black mass (0.7 × 0.7 × 0.6 cm) in the conjunctiva. A biopsy was taken. The biopsy showed malignant epithelioid cells...