Background: Iodine deficiency disorders (IDD) has been recognized as a public health problem in India. Surveys conducted in various states show that no state in the country is free from IDD. Since the program of Salt Iodization has been in progress for many decades, it is imperative to carry out Goiter surveys in the community on periodic basis to see the impact. The current study is part of a ...

BACKGROUND Endemic goiter is present in most parts of Iran. Iron deficiency adversely affects the physiology of thyroid. The initial steps of thyroid hormone synthesis are catalyzed by thyroperoxidases and are dependent on iron. In many developing countries, children are at high risk of both goiter and iron deficiency anemia. In addition, iron deficiency may alter central nervous system control...

The unfolded protein response (UPR) is an intracellular signaling pathway that regulates the protein folding and processing capacity of the endoplasmic reticulum (ER). The UPR is induced by the pharmacological agents that perturb ER functions but is also activated upon excessive accumulation of the mutant secretory proteins that are unable to attain correct three-dimensional structure and are t...

BACKGROUND Some studies have shown the possible role of protein-energy malnutrition (PEM) in persistence of endemic goiter in iodine replenished areas. The present study was conducted to assess the association between PEM and goiter in schoolchildren of Isfahan, Iran. METHODS In a cross-sectional study using multistage cluster random-sampling, 2331 schoolchildren with age ranged from 6-13 yea...

BACKGROUND Some of the thyroid disorders (TD) and Myasthenia gravis (MG) are autoimmune related disease. The purpose of the study to evaluate the relationship of MG with all morphological and functional thyroid disorders. METHODS We constructed a population-based cohort study during the period from January 2000-December 2002 by using reimbursement data from the Bureau National Health Insuranc...

UNLABELLED Anti-tumor necrosis factor (TNF)-α therapy is established as a new standard for the treatment of various autoimmune inflammatory diseases. We report the first case showing subacute thyroiditis-like symptoms with an amyloid goiter after anti-TNF-α therapy. A 56-year-old man with Crohn's disease presented with fever and a diffuse, tender goiter. To control the diarrhea, anti-TNF therap...

in the fall of 1991, the incidence of goiter was determined in i07x male and female school children in kermanshah city. the study was considered from two view points i.e., clinical examinations and measurements of levels of iodine excreted in urine, and was performed in three age groups: 7-11 years of age, 12-15 years of age and 16-18 years of age. clinical examination showed 16.5% occurrence o...

The study was conducted to determine the prevalence of goiter and hypothyroidism in two groups of the population at various stages of social development and to determine its association with malnutrition and dietary intake. Aboriginal inhabitants (Orang Asli), a resettlement rural village (Betau Post), a traditional village in the jungle (Lanai Post) and a modern village settlement near Kua...