نتایج جستجو برای: conformational variation

تعداد نتایج: 333759  

Liquid protein formulations are prone to form aggregates. The effect of nonionic surfactants such as Polysorbate 20 (PS 20) and n-Dodecyl β-D-maltoside (DDM) on the prevention of aggregation and conformational changes of recombinant human IFNβ-1b (rhIFN β_1b) was explored. Polysorbate has been used in formulations of protein pharmaceuticals. There have been concerns about using PS 20 due to its...

Journal: :Molecular Simulation 2021

Two-dimensional (2D) semiflexible polymers exhibit distinctive conformational and dynamical behaviour compared to the corresponding bulk polymers. Understanding microscopic origins of this char...

پایان نامه :0 1374

in fact this study is concerned with the relationship between the variation in thematice structure and the comprehension of spoken language. so the study focused on the following questions: 1. is there any relationship between thematic structure and the comprehension of spoken language? 2. which of the themes would have greated thematic force and be easier for the subjects to comprehend? accord...

Journal: :Digital discovery 2022

Contemporary molecular spectroscopy allows the study of flexible molecules, whose conformational behavior is ruled by flat potential energy surfaces (PESs) involving a large number minima with comparable stability.

Liquid protein formulations are prone to form aggregates. The effect of nonionic surfactants such as Polysorbate 20 (PS 20) and n-Dodecyl β-D-maltoside (DDM) on the prevention of aggregation and conformational changes of recombinant human IFNβ-1b (rhIFN β_1b) was explored. Polysorbate has been used in formulations of protein pharmaceuticals. There have been concerns about using PS 20 due to its...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم ریاضی و مهندسی کامپیوتر 1392

heuristics are often used to provide solutions for flow shop scheduling problems.the performance of a heuristic is usually judged by comparing solutions and run times on test cases.this investigation proposes an analytical alternative ,called asymptotic convergence ,which tests the convergence of the heuristic to a lower bound as problem size grows. the test is a stronger variation of worst cas...

Journal: :physical chemistry research 0
hooriye yahyaei department of chemistry, zanjan branch, islamic azad university, zanjan, iran seyede negar mousavi department of nanochemistry, faculty of pharmaceutical chemistry, pharmaceutical sciences branch, islamic azad university ,tehran - iran (iaups )

in this research, we report the results of dft calculations using xc-hybrid functional, b3lyp and employ nbo interpretation to investigate the stereoelectronic effects. electrostatic and steric impacts on the conformational properties of 1,2-difluorodiazene (1), 1,2-dichlorodiazene (2) and 1,2-dibromodiazene (3) are also studied. factors determining the thermodynamically stable molecular struct...

Journal: :Soft Matter 2021

The coupling between the ionization and conformational properties of two IDPs, histatin-5 ?-amyloid 42, in presence neutral charged crowders is studied by performing semi-grand canonical Monte Carlo simulations.

Journal: :Cell Structure and Function 1999

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