Baloxavir marboxil is a creative antiviral drug for influenza A and B viruses with novel mechanism of action. In this study, three series comprising total 21 previously unreported target compounds were designed synthesized. The drug-likeness these was evaluated by molecular docking, PAINS-Remover SwissADME. inhibitory effect affinity the on cap-dependent endonuclease activity virus evaluated. C...
