In an attempt to determine the presence or absence of correlation between the intraocular pressure-increasing and pupil-dilating effects of corticosteroids, the effect of topically applied dexamethasone and various autonomic agents has been studied in 12 hospitalised, healthy, young adult volunteers. Dexamethasone caused an average increase of intraocular pressure of 8-8 mmHg and of pupillary d...

Axonal transport in primate optic nerve axons was studied by autoradiography, scintillation counting, and electron microscopy under conditions of short-term intraocular pressure elevation. With elevation of intraocular pressure to 30 mm. Hg below mean arterial blood pressure, blockage of transport was detected within 2 hours by autoradiography and within 1 hour by electron microscopy. The earli...

The relationship of the ophthalmic pulse amplitude to the intraocular pressure has been described in rabbits and dogs. The effect of a suction cup on the intraocular pressure has been investigated in rabbit eyes and human eyes. Sample pulse tracings have been obtained using a suction cup on rabbits and man. Two estimates were made of the volume changes associated with the ophthalmic pulse xoave...

Background/aims—Mechanical forces are thought to induce cellular responses through activation of signalling pathways. Cells within the intraocular environment are exposed to constant changes in the levels of intraocular pressure. In this study, an attempt was made to determine the acute eVects of elevated hydrostatic pressure on diVerent intraocular cells

OBJECTIVE Clear corneal cataract incisions without sutures allow for rapid visual rehabilitation after phacoemulsification but might be associated with an increased risk of postoperative infection. The goal of this study was to examine in vitro dynamic changes in unhealed clear corneal cataract incisions that might adversely affect the risk of intraocular infection. DESIGN Laboratory investig...

Method: Cataract surgery was performed after controlling the intraocular pressure in patients presenting with acute phacomorphic glaucoma. Intraocular lenses were inserted in the bag after conventional extracapsular cataract extraction. Patients with minimum follow up of one year were analyzed for the study. Corrected visual acuity, intraocular pressure and any complications of surgery were rec...

although measurement of intracranial pressure by noninvasive methods has been suggested, but mainly invasive methods are used for this purpose-increase in episcleral venous pressure can be expected to result in a linear increase in intraocular pressure. congested oculat veins with capillary leakage and hemorrhage are seen when the icp is increased, thus theoretically measurement of intraocular ...

BACKGROUND The intraocular pressures and biomechanical parameters measured by the ocular response analyzer make the analyzer a useful tool for the diagnosis and management of anterior segment disease. This observational study was designed to investigate the effect of topical anesthesia on the parameters measured by the ocular response analyzer: corneal hysteresis, corneal resistance factor, Gol...

Tritiated leucine was injected into the vitreous of owl monkeys (Aotus trivirgatus) to make it available to retinal ganglion cells for protein synthesis. Intraocular pressure was maintained for eight hours at selected levels between 15 and 105 mm. Hg. Autoradiography and scintillation counting were used to follow the movement of the labeled protein along the axons from the retinal ganglion cell...