Clonidine hydrochloride is an antihypertensive agent used for migraine prophylaxis, attention deficit hyperactivity disorder, menopausal flushing and Tourette syndrome. The quantity of the active substance in pharmaceutical preparations must be within specific limits, in agreement with the respective label claim. Therefore, the aim of this study was to establish the conditions for two spectroph...

Production planning includes complex topics of production and operation management that according to expansion of decision-making methods, have been considerably developed. Nowadays, Managers use innovative approaches to solving problems of production planning. Given that the production plan is a type of prediction, models should be such that the slightest deviation from their reality. In this ...

Determination of terazosin hydrochloride dihydrate (TRZ) in drug substance and tablets was studied by fluorimetric techniques. The fluorimetric methods are based on: (1) measurement of the native fluorescence of the drug in water at 750 nm after excitation at 330 nm. (2) sensitizing the native fluorescence by formation a binary complex of drug with aqueous uranyl acetate (0.1% w/v) at the same ...

Objective: Ecosystems with mixed species compared to the ones with pure compositions provide a broader range of options in the fields of biodiversity, conservation, protection and restoration. Nearly all forest plantations are established as monocultures, but research has shown that there are potential advantages to be gained by using carefully designed species mixtures in place of monocultures...

In according to quantity of various consumption materials in construction sites of complex projects such as oil industry, infrastructure, and large scale commercial, management and monitoring of materials can affect on the final time and cost of project’s activities. In today’s world of rising labor costs and labor shortages, automated materials tracking can provide some advantage to impr...

BACKGROUND Parents' knowledge influences decisions regarding medical care for their children. METHODS Parents of pediatric primary care patients aged 9-14 years, irrespective of height, participated in open focus groups (OFGs). Moderators asked the question, 'How do people find out about growth hormone (GH)?' Because many parents cited the Internet, the top 10 results from the Google searches...

Airborne light detection and ranging (lidar) has become a powerful support for acquiring geospatial data in numerous geospatial applications and analyses. However, the process of extracting ground points accurately and effectively from raw point clouds remains a big challenge. This study presents an improved top-hat filter with a sloped brim to enhance the robustness of ground point extraction ...

We present a novel dynamic network interdiction model that accounts for interactions between an interdictor deploying resources on arcs in a digraph and an evader traversing the network from a designated source to a known terminus, wherein the agents may modify strategies in selected subsequent periods according to respective decision and implementation cycles. For the resulting minimax model, ...

Measurements of the iron regulatory hormone hepcidin by various methodologies and laboratories are not harmonized. As a result different numeric results are obtained for the same clinical sample. We investigated whether better agreement between plasma hepcidin methods can be achieved by harmonization. Native plasma pools (n = 11) of a variety of hepcidin concentrations and blank plasma spiked w...

The FASD study gathered 1330 answers about fun and software development from open source developers as well as 114 answers from programmers working in commercial software projects. The analysis of these data proves that fun plays an important role when software developers decide to get engaged in an open source project. Moreover, the comparison of the answers gives evidence for the hypothesis t...