www.thelancet.com Published online May 15, 2013 http://dx.doi.org/10.1016/S0140-6736(13)60984-8 1 Some therapies licensed to treat osteoporosis work by inhibiting bone turnover (anticatabolic agents) and some by stimulating bone formation (anabolic agents). In The Lancet, Joy Tsai and colleagues report an exciting new approach in which an anticatabolic drug, denosumab, is combined with an anabo...

In this report, we advocate an approach to combine formal specification components. Our work aims at building or reusing specification components, and compose them with a gluing language constituted of a minimal but sufficient set of operators. The glue allows to have at one’s disposal a global formal specification with heterogeneous components as basic entities. The interests are manifold: mod...

Recent experiments indicate the need for revision of a model of spatial memory consisting of viewpoint-specific representations, egocentric spatial updating and a geometric module for reorientation. Instead, it appears that both egocentric and allocentric representations exist in parallel, and combine to support behavior according to the task. Current research indicates complementary roles for ...

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A general method to combine several estimators of the same quantity is investigated. In the spirit of model and forecast averaging, the final estimator is computed as a weighted average of the initial ones, where the weights are constrained to sum to one. In this framework, the optimal weights, minimizing the quadratic loss, are entirely determined by the mean square error matrix of the vector ...

1. Challenges of Using Multimedia In the last decade, advanced computer technology has allowed for development of information systems and learning environments that combine language with other forms of human communication in innovative ways. Language in the form of written texts, for example, can be combined not only with static pictures or graphs as in printed material, but also with animation...

We devise a ternary operation for combining three quantum states: it consists of permuting the input systems in a continuous fashion and then discarding all but one of them. This generalizes a binary operation recently studied by Audenaert et al. [ADO16] in the context of entropy power inequalities. Our ternary operation continuously interpolates between all such nested binary operations. Our c...